SCHEMBL10124341

SCHEMBL10124341

CC(C)CC(C)(C(=O)OCCN(C)C)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.43
CHRM2 P08172 3/20 0.43
CHRM3 P20309 3/20 0.43
CHRM4 P08173 2/20 0.43
CHRM5 P08912 2/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
DNM1 Q05193 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MMP8 P22894 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PHLPP2 Q6ZVD8 1/20 0.34
POLB P06746 1/20 0.34
BCHE P06276 2/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18560733 0.86 MMP8 (0.41) MMP8
SCHEMBL17325882 0.84 CHRM2 (0.48) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL10124438 0.83 CHRM1 (0.43) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL19902135 0.83 CHRM1 (0.46) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL26338964 0.83 CHRM1 (0.46) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL17325884 0.83 CHRM2 (0.38) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL14421136 0.81 MMP8 (0.38) ALDH1A1MMP8
SCHEMBL807035 0.81 MMP8 (0.41) CHRM1ALDH1A1MMP8
SCHEMBL17325883 0.80 CHRM2 (0.36) CHRM1CHRM2CHRM3CHRM4CHRM5
SCHEMBL17325879 0.80 CHRM2 (0.42) CHRM1CHRM2CHRM3CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723990-B2 Library of pH responsive polymers and nanoprobes thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-08-15 US disclosed
US-20230127537-A1 PHOTOSENSITIVE COMPOSITION, NEGATIVE PHOTOSENSITIVE COMPOSITION, PIXEL DIVISION LAYER AND ORGANIC EL DISPLAY DEVICE TORAY INDUSTRIES, INC. (JP) 2023-04-27 US disclosed
US-20220163884-A1 COMPOSITION, FILM, OPTICAL FILTER AND METHOD FOR MANUFACTURING THE SAME, SOLID-STATE IMAGING ELEMENT, INFRARED SENSOR, AND SENSOR MODULE FUJIFILM CORPORATION (JP) 2022-05-26 US disclosed
US-20200333357-A1 NOVEL TFEB PATHWAY AGONISTS FOR METABOLIC DISEASES AND AGEING THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-10-22 US disclosed
US-20180201828-A1 Proppant Comprising Swellable Coating Thereon for Treatment of Subterranean Formations HALLIBURTON ENERGY SERVICES, INC. (US) 2018-07-19 US disclosed
US-10012902-B2 Positive resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
US-20170242339-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-24 US disclosed
US-20170143852-A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2017-05-25 US disclosed
WO-2015188157-A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-12-10 WO disclosed
EP-2420871-A1 POLYMERIZABLE COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND SOLID IMAGING ELEMENT FUJIFILM Corporation (JP) 2012-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200333357-A1 NOVEL TFEB PATHWAY AGONISTS FOR METABOLIC DISEASES AND AGEING TFEB, GPR119, SQSTM1 CHRM1 4146/4885CHRM2 3948/4885CHRM3 4235/4885
US-20170143852-A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF MSN, CD44, CD47 CHRM1 4328/4885CHRM2 4022/4885CHRM3 3699/4885
US-11723990-B2 Library of pH responsive polymers and nanoprobes thereof MSN, CD44, CD47 CHRM1 4328/4885CHRM2 4022/4885CHRM3 3699/4885
US-10012902-B2 Positive resist composition and pattern forming process EWSR1, SRPRA, SRPRB CHRM1 4367/4885CHRM2 4556/4885CHRM3 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.