SCHEMBL10128586

SCHEMBL10128586

Cc1cccc(N(c2ccccc2)c2ccc(N(c3ccccc3)c3cccc(C)c3)c3ccccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
SIGMAR1 Q99720 2/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ALDH1A1 P00352 4/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
JAK2 O60674 1/20 0.38
HTT P42858 1/20 0.38
PAX8 Q06710 1/20 0.38
THRB P10828 1/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 3/20 0.36
ALOX15 P16050 3/20 0.36
USP2 O75604 2/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128581 0.96 ACHE (0.42) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL13242040 0.95 SIGMAR1 (0.37) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL7482902 0.93 HSD17B1 (0.39) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL7081739 0.91 ALDH1A1 (0.35) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL10066739 0.89 SIGMAR1 (0.38) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL13006217 0.89 SIGMAR1 (0.35) ACHESIGMAR1SLC6A2SLC6A4ALDH1A1
SCHEMBL12249724 0.88 SIGMAR1 (0.46) ACHESIGMAR1ALDH1A1RAB9ANPC1
SCHEMBL14552156 0.88 RXRA (0.41) SIGMAR1SLC6A2SLC6A4ALDH1A1RAB9A
SCHEMBL7085931 0.88 RXRA (0.41) SIGMAR1SLC6A2SLC6A4ALDH1A1RAB9A
SCHEMBL7086068 0.88 RXRA (0.41) SIGMAR1SLC6A2SLC6A4ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210104680-A1 ORGANIC ELECTROLUMINESCENT ELEMINT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2021-04-08 US disclosed
US-10910565-B2 Organic electroluminescent element, material for organic electroluminescent elements, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-02-02 US disclosed
US-10243145-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-20180212152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180212152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-9960358-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960358-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20170301863-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2017-10-19 US disclosed
US-20170301863-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2017-10-19 US disclosed
US-9728727-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2017-08-08 US disclosed
US-20090058270-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-05 US disclosed
US-20080206447-A1 ORGANIC-ELECTROLUMINESCENCE-MATERIAL-CONTAINING SOLUTION, METHOD FOR FORMING ORGANIC ELECTROLUMINESCENCE THIN FILM AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-28 US disclosed
US-20080206447-A1 ORGANIC-ELECTROLUMINESCENCE-MATERIAL-CONTAINING SOLUTION, METHOD FOR FORMING ORGANIC ELECTROLUMINESCENCE THIN FILM AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-28 US disclosed
EP-1926159-A1 ASYMMETRIC FLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 2008-05-28 EP disclosed
US-20080001123-A1 Luminescent Ink Composition for Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD (JP) 2008-01-03 US disclosed
US-20080001123-A1 Luminescent Ink Composition for Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD (JP) 2008-01-03 US disclosed
US-20070237984-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
US-20070237984-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
US-20070207343-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-09-06 US disclosed
US-20070207343-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243145-B2 Organic electroluminescence device and organic light emitting medium TRPA1, EPM2A, KCNN2 ACHE 682/4885SIGMAR1 2735/4885SLC6A2 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.