SCHEMBL1013408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL525877	0.77	MAPT (0.59)	PARP1BACE1NOTUM
	SCHEMBL4872103	0.76	GAA (0.60)	DAOKDRNOTUM
	SCHEMBL16060851	0.76	PDE3B (0.45)	NOTUMCYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL6551744	0.73	KIF11 (0.45)	KIF11DAOTNKSPARP1BACE1
	SCHEMBL8987298	0.70	HPGD (0.68)	KIF11TNKSPARP1WNT3ATNKS2
	SCHEMBL17840160	0.69	KIF11 (0.68)	KIF11BACE1MAOBPSEN1PSEN2
	SCHEMBL1725632	0.68	KIF11 (0.47)	KIF11TNKSPARP1BACE1TDP2
	SCHEMBL8025255	0.68	KIF11 (0.65)	KIF11BACE1MAOBPSEN1PSEN2
	SCHEMBL16652113	0.67	ALDH1A1 (0.61)	KIF11DAOTNKSPARP1WNT3A
	SCHEMBL23796086	0.66	HPGD (0.45)	KIF11TNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.