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SCHEMBL10138847

SCHEMBL10138847

COc1ccc(Br)c(C)c1Oc1c(C)cc(OC)c(OC)c1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB1 Q9H4B7 4/20 0.39
▸ NQO2 P16083 4/20 0.39
▸ L3MBTL1 Q9Y468 5/20 0.38
▸ MAPT P10636 4/20 0.38
▸ LMNA P02545 2/20 0.38
▸ HPGD P15428 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ ACHE P22303 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ PPARG P37231 1/20 0.35
▸ NCOA2 Q15596 1/20 0.35
▸ NCOA1 Q15788 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ CA2 P00918 1/20 0.34
▸ CA4 P22748 1/20 0.34
▸ TUBB4A P04350 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431072 0.79 TUBB1 (0.42) TUBB1NQO2L3MBTL1MAPTLMNA
SCHEMBL772484 0.75 CA2 (0.50) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL30171329 0.75 CA2 (0.50) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL9292546 0.73 NQO2 (0.42) TUBB1NQO2MAPTMAPK1ACHE
SCHEMBL1243920 0.73 ACHE (0.56) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL30835564 0.73 ACHE (0.56) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL147312 0.72 TUBB1 (0.46) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL9352550 0.72 ACHE (0.50) TUBB1NQO2L3MBTL1MAPTACHE
SCHEMBL677634 0.72 ACHE (0.50) TUBB1NQO2MAPTACHEALDH1A1
SCHEMBL1829968 0.71 NQO2 (0.44) TUBB1NQO2L3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190174759-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2019-06-13 — — US disclosed
US-10244755-B2 Fungicidal active compound combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-02 — — US disclosed
EP-1802197-B1 FUNGICIDAL COMBINATIONS OF ACTIVE INGREDIENTS BAYER IP GMBH (DE) 2018-02-28 — — EP disclosed
US-20180014541-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS ARYSTA LIFESCIENCE CORPORATION (JP) 2018-01-18 — — US disclosed
US-20180014541-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS ARYSTA LIFESCIENCE CORPORATION (JP) 2018-01-18 — — US disclosed
US-9844220-B2 Synergistic fungicidal active substance combinations FMC CORPORATION (US) 2017-12-19 — — US disclosed
US-9844220-B2 Synergistic fungicidal active substance combinations FMC CORPORATION (US) 2017-12-19 — — US disclosed
US-9717247-B2 Synergistic fungicidal active combinations BAYER CROPSCIENCE AG (DE) 2017-08-01 — — US disclosed
US-9717247-B2 Synergistic fungicidal active combinations BAYER CROPSCIENCE AG (DE) 2017-08-01 — — US disclosed
US-9414600-B2 Active compound combinations BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-16 — — US disclosed
US-20090018015-A1 Synergistic Fungicidal Active Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-15 — — US disclosed
US-20090018015-A1 Synergistic Fungicidal Active Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-01-15 — — US disclosed
US-20080269051-A1 For controlling phytopathogenic fungi BAYER CORPSCIENCE AG (DE) 2008-10-30 — — US disclosed
US-20080269051-A1 For controlling phytopathogenic fungi BAYER CORPSCIENCE AG (DE) 2008-10-30 — — US disclosed
US-20070298966-A1 Fungicidal Combinations of Active Ingredients BAYERCROPSCIENCE AG (DE) 2007-12-27 — — US disclosed
US-20070298966-A1 Fungicidal Combinations of Active Ingredients BAYERCROPSCIENCE AG (DE) 2007-12-27 — — US disclosed
WO-2007134778-A2 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-11-29 — — WO disclosed
WO-2007110173-A2 FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-10-04 — — WO disclosed
WO-2007104437-A1 FUNGICIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2007-09-20 — — WO disclosed
US-20070060579-A1 Synergistic fungicidal active substance combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190174759-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS DDT, CYP4X1, CYP51A1 TUBB1 2681/4885NQO2 617/4885L3MBTL1 1603/4885
US-20090018015-A1 Synergistic Fungicidal Active Combinations CYP51A1, CYP1A2, CYP3A7 TUBB1 356/4885NQO2 171/4885L3MBTL1 1385/4885
US-10244755-B2 Fungicidal active compound combinations DDT, CYP4X1, CYP51A1 TUBB1 2681/4885NQO2 617/4885L3MBTL1 1603/4885
US-20080269051-A1 For controlling phytopathogenic fungi ERG28, CYP4X1, PFN1 TUBB1 1060/4885NQO2 1009/4885L3MBTL1 3307/4885
US-20070060579-A1 Synergistic fungicidal active substance combinations CYP51A1, CYP1A2, CYP4X1 TUBB1 161/4885NQO2 430/4885L3MBTL1 2335/4885
US-20180014541-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS CYP4X1, ERG28, CASP1 TUBB1 1172/4885NQO2 925/4885L3MBTL1 3126/4885
US-20070298966-A1 Fungicidal Combinations of Active Ingredients DDT, CYP51A1, CYP4Z1 TUBB1 2534/4885NQO2 424/4885L3MBTL1 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.