Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | HPGD | P15428 | 2/20 | 0.84 |
| ▸ | RECQL | P46063 | 2/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | COMT | P21964 | 3/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144550 | 0.91 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL31618898 | 0.91 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL11202635 | 0.84 | ALDH1A1 (0.85) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL10144273 | 0.83 | MAPT (0.84) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL10144263 | 0.82 | EGFR (0.78) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL8848276 | 0.78 | FTO (0.74) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL8848272 | 0.78 | FTO (0.74) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL8848281 | 0.78 | FTO (0.74) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL20100865 | 0.78 | FTO (0.74) | ALDH1A1MAPTHPGDRECQLMEN1 | |
| SCHEMBL15920344 | 0.77 | FTO (0.73) | ALDH1A1MAPTHPGDRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | ALDH1A1 1572/4885MAPT 3699/4885HPGD 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.