SCHEMBL10150940

SCHEMBL10150940

C[Si](C)(Cl)C(CC(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 7/20 0.40
SLC6A3 Q01959 2/20 0.40
CACNA1F O60840 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
ADRA2B P18089 1/20 0.40
CHRM3 P20309 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRK1 P41145 1/20 0.40
CACNA1D Q01668 1/20 0.40
KCNH2 Q12809 1/20 0.40
CACNA1S Q13698 1/20 0.40
CACNA1C Q13936 1/20 0.40
SCN5A Q14524 1/20 0.40
HTR2A P28223 6/20 0.39
TAAR1 Q96RJ0 3/20 0.38
GRM2 Q14416 1/20 0.38
GRM3 Q14832 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523287 0.81 LMNA (0.45) HRH1HTR2ATAAR1TSHRAOC3
SCHEMBL9838705 0.76 HTR2A (0.58) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL18662236 0.71 HRH1 (0.43) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL18662207 0.71 HRH1 (0.43) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL3794550 0.70 LMNA (0.46) HRH1HTR2ATAAR1TDP1TSHR
SCHEMBL15023661 0.69 AOC3 (0.41) HRH1OPRK1HTR2ATAAR1TSHR
SCHEMBL4086098 0.69 TSHR (0.48) HRH1SLC6A3HTR2ATAAR1TDP1
SCHEMBL3799465 0.69 ADRA2A (0.43) SLC6A3TAAR1TSHRAOC3LMNA
SCHEMBL10338733 0.68 RIPK1 (0.33) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL9493121 0.67 HRH1 (0.54) HRH1SLC6A3CACNA1FCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140284306-A1 METHOD FOR MANUFACTURING POROUS STRUCTURE AND METHOD FOR FORMING PATTERN KABUSHIKI KAISHA TOSHIBA (JP) 2014-09-25 US disclosed
US-8778201-B2 Method for manufacturing porous structure and method for forming pattern KABUSHIKI KAISHA TOSHIBA (JP) 2014-07-15 US disclosed
US-8435416-B2 Method for manufacturing porous structure and method for forming pattern KABUSHIKI KAISHA TOSHIBA (JP) 2013-05-07 US disclosed
US-8394877-B2 Method for manufacturing porous structure and method for forming pattern KABUSHIKA KAISHA TOSHIBA (JP) 2013-03-12 US disclosed
US-20120037594-A1 METHOD FOR MANUFACTURING POROUS STRUCTURE AND METHOD FOR FORMING PATTERN ASAKAWA KOJI (JP) 2012-02-16 US disclosed
US-20120041121-A1 METHOD FOR MANUFACTURING POROUS STRUCTURE AND METHOD FOR FORMING PATTERN ASAKAWA KOJI (JP) 2012-02-16 US disclosed
US-20120037595-A1 METHOD FOR MANUFACTURING POROUS STRUCTURE AND METHOD FOR FORMING PATTERN ASAKAWA KOJI (JP) 2012-02-16 US disclosed
US-8043520-B2 Method for manufacturing porous structure and method for forming pattern KABUSHIKI KAISHA TOSHIBA (JP) 2011-10-25 US disclosed
US-20090130380-A1 METHOD FOR MANUFACTURING POUROUS STRUCTURE AND METHOD FOR FORMING PATTERN ASAKAWA KOJI 2009-05-21 US disclosed
US-7517466-B2 Method for manufacturing porous structure and method for forming pattern KABUSHIKI KAISHA TOSHIBA (JP) 2009-04-14 US disclosed