Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99169 | 0.91 | CASP6 (0.44) | CASP6MAPTGAAALDH1A1LMNA | |
| SCHEMBL11703945 | 0.83 | TSHR (0.49) | CASP6MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6742322 | 0.83 | GSK3B (0.57) | CASP6MAPTGAAALDH1A1LMNA | |
| SCHEMBL2875677 | 0.82 | VCAM1 (0.64) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7399156 | 0.82 | ALDH1A1 (0.47) | CASP6MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL15505486 | 0.82 | TSHR (0.67) | MAPTGAAALDH1A1KMT2ATSHR | |
| SCHEMBL3143253 | 0.82 | LMNA (0.67) | CASP6MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL3143262 | 0.82 | LMNA (0.67) | CASP6MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL6746842 | 0.81 | VCAM1 (0.46) | CASP6MAPTGAAALDH1A1LMNA | |
| SCHEMBL1185712 | 0.81 | MAPT (0.49) | CASP6MAPTGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072734-B2 | Quaternary ammonium salt compounds | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| CN-102459231-A | Quaternary ammonium salt compound | TEIJIN PHARMA LTD | 2012-05-16 | — | — | CN | disclosed |
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | TEIJIN PHARMA LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-0326307-B1 | Novel pyridazinone derivatives and pharmaceutical preparations containing them | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5063227-A | QUINAZOLINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES HAVING CARDIOTONIC ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0326307-A2 | Novel pyridazinone derivatives and pharmaceutical preparations containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0001051-B1 | DERIVATIVES OF BENZENESULFONAMIDE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-11 | — | — | EP | disclosed |
| US-4235918-A | SALIDIURETICS, TREATMENT OF HYPERTONIC CONDITIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| EP-0001051-A2 | Derivatives of benzenesulfonamide, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-03-21 | — | — | EP | disclosed |
| US-4082843-A | 3-(3-(3-Substituted amino-2-hydroxypropoxy)phenyl)-6-hydrazino pyridazines and their use as vasodilators and β-adrenergic blocking agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | ADRB2, AGTR2, ADRB3 | CASP6 4850/4885MAPT 2879/4885GAA 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.