Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199721 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7457064 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9521855 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9201276 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL6571622 | 0.92 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7459977 | 0.90 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9521181 | 0.90 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9521191 | 0.90 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL10600188 | 0.88 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9663206 | 0.88 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324130-B2 | Synergistic active ingredient combinations | BAYER CROPSCIENCE AG (DE) | 2012-12-04 | — | — | US | disclosed |
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | BAYER CROPSCIENCE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| US-8039013-B2 | Mixture containing spiroxamine , a azole and carboxamide | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | disclosed |
| US-20110218100-A1 | Synergistic Fungicidal Active Compound Combinations Containing a Carboxamide, an Azole, a Second Azole or a Strobilurin | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110152097-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2279664-A1 | Agent combinations | Bayer CropScience AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| WO-2011006603-A2 | SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS CONTAINING PHENYL TRIAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-01-20 | — | — | WO | disclosed |
| EP-2272368-A1 | Agent combinations | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-2132989-A2 | Agent combinations | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |
| US-20090286681-A1 | Synergistic Fungicidal Active Compounde Combinations Containing a Carboxamide, an Azole, a Second Azole or a Strobilurin | BAYER CROPSCIENCE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| US-20090280981-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090227540-A1 | TREATMENT OF WOOD BASED ON NOVEL FORMULATIONS OF BORATRANES | TAPUAE PARTNERSHIP (NZ) | 2009-09-10 | — | — | US | disclosed |
| WO-2009012907-A1 | SYNERGISTIC FUNGICIDAL ACTIVE GENISTEIN COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | WO | disclosed |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-2000028-A1 | Fungicidal active agent compounds | Bayer CropScience Aktiengesellschaft (DE) | 2008-12-10 | — | — | EP | disclosed |
| US-20080269263-A1 | Synergistic Fungidical Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269051-A1 | For controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| WO-2008092580-A2 | SYNERGISTIC FUNGICIDAL COMBINATIONS COMPRISING FORMONONETIN | BAYER CROPSCIENCE AG (DE) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152097-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | CYP3A4 1609/4885CYP2C9 1524/4885CYP2C19 2637/4885 |
| US-20080269263-A1 | Synergistic Fungidical Active Substance Combinations | ERG28, MANBA, MAN2A1 | CYP3A4 483/4885CYP2C9 1225/4885CYP2C19 1054/4885 |
| US-20090018015-A1 | Synergistic Fungicidal Active Combinations | CYP51A1, CYP1A2, CYP3A7 | CYP3A4 6/4885CYP2C9 10/4885CYP2C19 28/4885 |
| US-20090227540-A1 | TREATMENT OF WOOD BASED ON NOVEL FORMULATIONS OF BORATRANES | BLVRB, BCHE, MGAM | CYP3A4 91/4885CYP2C9 476/4885CYP2C19 1487/4885 |
| US-20120035050-A1 | Synergistic Combinations Of Active Ingredients | C1S, MAN2B1, MANBA | CYP3A4 1716/4885CYP2C9 2923/4885CYP2C19 3507/4885 |
| US-20110218100-A1 | Synergistic Fungicidal Active Compound Combinations Containing a Carboxamide, an Azole, a Second Azole or a Strobilurin | SUCLG1, ERG28, ME2 | CYP3A4 594/4885CYP2C9 633/4885CYP2C19 876/4885 |
| US-20080269051-A1 | For controlling phytopathogenic fungi | ERG28, CYP4X1, PFN1 | CYP3A4 113/4885CYP2C9 460/4885CYP2C19 662/4885 |
| US-20110166109-A1 | Synergistic Active Compound Combinations Comprising Phenyltriazoles | NAT1, ACAT1, CAT | CYP3A4 175/4885CYP2C9 1522/4885CYP2C19 2517/4885 |
| US-20120015910-A1 | Synergistic fungicidal active substance combinations | CYP51A1, CYP1A2, CYP4X1 | CYP3A4 22/4885CYP2C9 61/4885CYP2C19 41/4885 |
| US-20090286681-A1 | Synergistic Fungicidal Active Compounde Combinations Containing a Carboxamide, an Azole, a Second Azole or a Strobilurin | MGAM, SUCLG1, MGAM2 | CYP3A4 398/4885CYP2C9 457/4885CYP2C19 567/4885 |
| US-20090280981-A1 | SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS | CYP51A1, ERG28, CYP4X1 | CYP3A4 24/4885CYP2C9 54/4885CYP2C19 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.