Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144181 | 0.82 | MAPT (0.49) | LMNASMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL3368306 | 0.77 | TRPA1 (0.55) | LMNASMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL10174986 | 0.74 | MAPT (0.53) | SMN1; SMN2ALDH1A1MAPTTEAD1TEAD4 | |
| SCHEMBL10144178 | 0.72 | MAPT (0.50) | LMNASMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL28248704 | 0.70 | TAS2R14 (0.63) | TAS2R14LMNADHODHHDAC6SMN1; SMN2 | |
| SCHEMBL10144581 | 0.69 | TAS2R14 (0.55) | TAS2R14SMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL30855351 | 0.69 | TAS2R14 (1.00) | TAS2R14LMNADHODHHDAC6TRPA1 | |
| SCHEMBL10536647 | 0.69 | TAS2R14 (1.00) | TAS2R14LMNADHODHHDAC6TRPA1 | |
| SCHEMBL10144180 | 0.67 | TRPA1 (0.40) | TAS2R14LMNASMN1; SMN2TRPA1ALDH1A1 | |
| SCHEMBL10144187 | 0.67 | PTGS2 (0.52) | LMNATRPA1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | TAS2R14 2542/4885LMNA 1164/4885DHODH 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.