Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.48 |
| ▸ | TEAD2 | Q15562 | 2/20 | 0.48 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144581 | 0.84 | TAS2R14 (0.55) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10144178 | 0.80 | MAPT (0.50) | MAPTRAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6211043 | 0.78 | MAPT (0.61) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22719582 | 0.78 | ALDH1A1 (0.61) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10144184 | 0.77 | APP (0.43) | MAPTRAB9AALDH1A1MEN1HTT | |
| SCHEMBL10144191 | 0.77 | APP (0.43) | MAPTRAB9AALDH1A1HTTKMT2A | |
| SCHEMBL1921484 | 0.77 | MAPT (0.77) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL21764739 | 0.75 | ALDH1A1 (0.61) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10174974 | 0.74 | TAS2R14 (0.52) | MAPTRAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18120683 | 0.73 | MAPT (0.67) | MAPTRAB9AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012278-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED (US) | 2012-01-26 | — | — | WO | disclosed |
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | MAPT 3699/4885RAB9A 2178/4885ALDH1A1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.