SCHEMBL10178744

SCHEMBL10178744

CCC(C)c1cccc(COCCOc2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
FFAR1 O14842 5/20 0.40
ADAMTS4 O75173 5/20 0.39
MMP13 P45452 5/20 0.39
LSS P48449 1/20 0.39
LTA4H P09960 1/20 0.39
BCHE P06276 1/20 0.38
RARA P10276 1/20 0.38
RARB P10826 1/20 0.38
PTGER4 P35408 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178709 0.89 FFAR1 (0.48) FFAR1ADAMTS4MMP13BCHE
SCHEMBL10178613 0.86 NPC1 (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL10178729 0.85 L3MBTL1 (0.54) BCHE
SCHEMBL10180887 0.84 KDM4E (0.37) FFAR1BCHEPTGER4
SCHEMBL10178573 0.83 KDM4E (0.48) PTGER4
SCHEMBL10178727 0.82 MAPT (0.45)
SCHEMBL10178653 0.80 BCHE (0.53) FFAR1BCHE
SCHEMBL10178628 0.80 TSHR (0.50) BCHE
SCHEMBL9793384 0.79 MAOB (0.48) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL10178751 0.78 FFAR1 (0.53) FFAR1LTA4HBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed