Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28776041 | 1.00 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| Sulfuric Acid SCHEMBL11090925 | 0.98 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL987086 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL42084 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| Hydrogen Peroxide SCHEMBL28115963 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698553 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698543 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL11360544 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9777404 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL10698540 | 0.97 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591707-B | High-temperature fast-curing starch-based shaving board adhesive and preparation method thereof | 江南大学 | 2022-12-13 | — | — | CN | claimed |
| CN-115433985-A | Aluminum alloy anodic oxide film low-nickel sealant, aluminum alloy anodic oxide film sealant solution and preparation method thereof | 武汉材料保护研究所有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-114591707-A | High-temperature fast-curing starch-based shaving board adhesive and preparation method thereof | 江南大学 | 2022-06-07 | — | — | CN | claimed |
| WO-2020131678-A1 | CLEANSING COMPOSITION AND METHOD | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2020-06-25 | — | — | WO | claimed |
| CN-110395861-A | A method of it is granulated using oily sludge | YIXING INNOVATION ENVIRONMENTAL PROT CO LTD | 2019-11-01 | — | — | CN | claimed |
| CN-110179681-A | A kind of nano silver shower cream and preparation method thereof for capableing of antibiotic and sterilizing | 得洁日化科技有限公司 | 2019-08-30 | — | — | CN | claimed |
| CN-109511655-A | A kind of bactericidal composition | 沈阳中化农药化工研发有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-105923898-B | A kind of honeycomb film column mould oxidative treatment dirt Organic substance in water equipment and its working method | 徐州工程学院 | 2019-03-22 | — | — | CN | claimed |
| CN-108394842-A | A kind of carbon tetrachloride special air blower replacement mechanism | 徐州工程学院 | 2018-08-14 | — | — | CN | claimed |
| CN-106495064-B | PLC dual controls lifting gear and its control method in a kind of high water-permeable brick production in sponge city | 江苏建筑职业技术学院 | 2018-06-26 | — | — | CN | claimed |
| CN-105284887-A | Washing disinfectant for sofa leather | MINGGUANG LIANGYU FURNITURE CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-103740491-A | Antibacterial laundry detergent and preparation process thereof | KINGDOM SANITARY PRODUCTS CO LTD GUANGDONG | 2014-04-23 | — | — | CN | claimed |
| EP-2365744-B1 | GEL PREVENTION AGENTS | AKZO NOBEL NV (NL) | 2013-01-02 | — | — | EP | claimed |
| CN-100523020-C | High performance organo-silicon modified vinyl acetate emulsion and its preparation | UNIV WUHAN (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-1887921-A | High performance organo-silicon modified vinyl acetate emulsion and its prepn | UNIV WUHAN (CN) | 2007-01-03 | — | — | CN | claimed |
| CN-1618866-A | Preparation method of polyvinyl chloride/inorganic rigid particle composite resin | UNIV HUADONG TECHNOLOGY (CN) | 2005-05-25 | — | — | CN | claimed |
| EP-0591771-A1 | A synthetic, mineral oil free, forming oil composition dispersed in a hydroalcoholic medium | CENTRO SVILUPPO MATERIALI S.p.A. (IT) | 1994-04-13 | — | — | EP | claimed |
| US-4759875-A | Oxo-derived mild surfactant blends | S. C. JOHNSON & SON, INC. (US) | 1988-07-26 | — | — | US | claimed |
| EP-0236677-A2 | Oxo-derived mild surfactant blends | S.C. JOHNSON & SON, INC. (US) | 1987-09-16 | — | — | EP | claimed |
| US-4692271-A | PUMPABLE MIXTURES; LAMELLAR PHASE | ALBRIGHT & WILSON LTD. (GB) | 1987-09-08 | — | — | US | claimed |