SCHEMBL1020070

SCHEMBL1020070

NCC(=O)OC1CCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.47
CYP19A1 P11511 2/20 0.46
EPHX1 P07099 2/20 0.44
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
STS P08842 4/20 0.35
BCHE P06276 1/20 0.35
TPSAB1 Q15661 2/20 0.35
TPSD1 Q9BZJ3 2/20 0.35
TPSG1 Q9NRR2 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
APOBEC3A P31941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18630264 0.98 CYP2C19 (0.53) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL75532 0.98 CYP2C19 (0.53) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL16439889 0.98 NAAA (0.48) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL23813855 0.98 CYP2C19 (0.53) NAAACYP2C19HTTCYP19A1EPHX1
Hydrochloric Acid SCHEMBL7309629 0.98 NAAA (0.48) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL23813782 0.98 CYP2C19 (0.53) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL18186688 0.98 CYP2C19 (0.53) NAAACYP2C19HTTCYP19A1EPHX1
Hydrochloric Acid SCHEMBL7309555 0.96 CYP2C19 (0.52) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL16439874 0.96 CYP2C19 (0.52) NAAACYP2C19HTTCYP19A1EPHX1
SCHEMBL16439937 0.96 CYP2C19 (0.52) NAAACYP2C19HTTCYP19A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340595-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LTD (GB) 2025-11-06 US claimed
US-20240391959-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LIMITED (GB) 2024-11-28 US claimed
US-20240382605-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2024-11-21 US claimed
EP-4408433-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF Ionis Pharmaceuticals, Inc. (US) 2024-08-07 EP claimed
US-11970555-B2 Bicyclic peptide ligands specific for transferrin receptor 1 (TfR1) BICYCLETX LIMITED (GB) 2024-04-30 US claimed
EP-4244235-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TFR1) BicycleTX Limited (GB) 2023-09-20 EP claimed
WO-2023056388-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-04-06 WO claimed
US-20220194988-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LIMITED (GB) 2022-06-23 US claimed
WO-2022101633-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LIMITED (GB) 2022-05-19 WO claimed
CN-103930437-A Potent and selective inhibitors of Nav1.3 and Nav1.7 AMGEN INC 2014-07-16 CN claimed
CN-103370331-A Amino statin derivatives for the treatment of arthrosis MERCK PATENT GMBH 2013-10-23 CN claimed
EP-0950046-B1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS NAEJA PHARMACEUTICAL INC (CA) 2002-04-10 EP claimed
EP-0961779-A1 SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS SYNPHAR LABORATORIES INC. (CA) 1999-12-08 EP claimed
EP-0950046-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (CA) 1999-10-20 EP claimed
WO-1998032766-A1 SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS SYNPHAR LABORATORIES INC. (US) 1998-07-30 WO claimed
WO-1998012176-A1 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS SYNPHAR LABORATORIES INC. (US) 1998-03-26 WO claimed
CN-1148393-A Bradykinin antagonist peptides incorporating N-substituted glycines CORTECH INC (US) 1997-04-23 CN claimed
US-12624358-B2 Compounds and methods for reducing PLN expression IONIS PHARMACEUTICALS, INC. (US) 2026-05-12 US disclosed
WO-1987002669-A1 PHOSPHINYLALKANOYL IMINO ACIDS SCHERING CORPORATION (US) 1987-05-07 WO disclosed
CN-86105218-A The preparation method of antiparasitic agents 1987-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970555-B2 Bicyclic peptide ligands specific for transferrin receptor 1 (TfR1) TFRC, FTH1, SLC40A1 NAAA 4682/4885CYP2C19 3736/4885HTT 408/4885
US-20240391959-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) TFRC, FTH1, SLC40A1 NAAA 4682/4885CYP2C19 3736/4885HTT 408/4885
US-20250340595-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) TFRC, FTH1, SLC40A1 NAAA 4682/4885CYP2C19 3736/4885HTT 408/4885
US-20220194988-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) TFRC, FTH1, SLC40A1 NAAA 4682/4885CYP2C19 3736/4885HTT 408/4885
US-12624358-B2 Compounds and methods for reducing PLN expression PHAX, ACTN1, ATP2A1 NAAA 3004/4885CYP2C19 4855/4885HTT 2731/4885
US-20240382605-A1 CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF DCLRE1B, PLK1, PAICS NAAA 4720/4885CYP2C19 4756/4885HTT 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.