Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18186688 | 1.00 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL23813782 | 1.00 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL75532 | 1.00 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL23813855 | 1.00 | CYP2C19 (0.53) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL16439887 | 0.98 | CYP2C19 (0.52) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| Hydrochloric Acid SCHEMBL7309555 | 0.98 | CYP2C19 (0.52) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL16439874 | 0.98 | CYP2C19 (0.52) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL16439937 | 0.98 | CYP2C19 (0.52) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| SCHEMBL1020070 | 0.98 | NAAA (0.50) | CYP2C19NAAAHTTCYP19A1EPHX1 | |
| Hydrochloric Acid SCHEMBL7309629 | 0.95 | NAAA (0.48) | CYP2C19NAAAHTTCYP19A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | MEDIBOSTON LIMITED (HK) | 2024-07-09 | — | — | US | disclosed |
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | FORTVITA BIOLOGICS LIMITED (CN) | 2021-09-16 | — | — | US | disclosed |
| CN-106061942-B | Novel CYP-eicosanoid derivatives | 分子医学马克斯德尔布吕克中心 | 2019-11-15 | — | — | CN | disclosed |
| CN-110072883-A | The relevant peptide of therapeutic MOTS-C | 科巴公司 | 2019-07-30 | — | — | CN | disclosed |
| EP-3252066-B1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2019-05-22 | — | — | EP | disclosed |
| US-20190100541-A1 | DIOXOLANE ANALOGUES OF URIDINE FOR THE TREATMENT OF CANCER | MEDIVIR AB (SE) | 2019-04-04 | — | — | US | disclosed |
| CN-109562083-A | CYP-eicosanoid analogs for treatment or prevention of diseases associated with neovascularization and/or inflammation | 奥迈科斯治疗公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108349880-A | The steady analog of CYP eicosanoid metabolics for treating heart disease | 奥迈科斯治疗公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105007990-B | The purposes of cosmetic composition from fish artemia hatching solution, its production method and its aesthetic appearance for being used to improving skin | 阿克生物科技公司 | 2018-04-06 | — | — | CN | disclosed |
| EP-3252066-A1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2017-12-06 | — | — | EP | disclosed |
| EP-3041855-B1 | HCV POLYMERASE INHIBITORS | MEDIVIR AB (SE) | 2017-07-26 | — | — | EP | disclosed |
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
| CN-1330712-A | Biogical compositions, components thereof and uses therefor | MELBOURNE HEALCH CARE LTD (AU) | 2002-01-09 | — | — | CN | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| CN-1175953-A | Novel dipeptide amidines as thrombin inhibitors | BASF AG (DE) | 1998-03-11 | — | — | CN | disclosed |
| CN-1173872-A | Thrombin inhibitors | BASF AG (DE) | 1998-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283125-A1 | CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF | TOP2A, TOP1, XPA | CYP2C19 1974/4885NAAA 2234/4885HTT 1033/4885 |
| US-12029736-B2 | Camptothecin derivatives and conjugates thereof | TOP2A, TOP1, XPA | CYP2C19 1974/4885NAAA 2234/4885HTT 1033/4885 |
| US-20190100541-A1 | DIOXOLANE ANALOGUES OF URIDINE FOR THE TREATMENT OF CANCER | ADORA3, DUT, NT5C | CYP2C19 1112/4885NAAA 4031/4885HTT 3787/4885 |
| US-20170073370-A1 | BROAD SPECTRUM ANTIBIOTICS | SPAST, NPEPPS, SPOUT1 | CYP2C19 4355/4885NAAA 115/4885HTT 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.