Nicocodine

Nicocodine

SCHEMBL1023092

COc1ccc2c3c1OC1C(OC(=O)c4cccnc4)C=CC4C(C2)N(C)CCC341

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 12/20 0.69
OPRK1 P41145 9/20 0.69
OPRD1 P41143 4/20 0.69
MRGPRX2 Q96LB1 3/20 0.62
ADRB1 P08588 1/20 0.62
PDE4D Q08499 1/20 0.62
PDE3A Q14432 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicocodine SCHEMBL159020 1.00 OPRM1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicocodine SCHEMBL29531263 1.00 OPRM1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL26237 0.94 OPRD1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL680036 0.94 OPRD1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL29408441 0.94 OPRD1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL29349768 0.94 OPRD1 (0.69) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL1649977 0.93 OPRD1 (0.68) OPRM1OPRK1OPRD1MRGPRX2ADRB1
Nicomorphine SCHEMBL395672 0.93 OPRD1 (0.68) OPRM1OPRK1OPRD1MRGPRX2ADRB1
SCHEMBL8418756 0.91 OPRM1 (0.76) OPRM1OPRK1OPRD1MRGPRX2ADRB1
SCHEMBL8769499 0.87 OPRM1 (0.75) OPRM1OPRK1OPRD1MRGPRX2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 EP claimed
US-11872307-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2024-01-16 US claimed
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 EP claimed
WO-2023205619-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-10-26 WO claimed
US-20220211616-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2022-07-07 US claimed
EP-3682872-A1 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2020-07-22 EP claimed
US-20070224129-A1 Anti-misuse microparticulate oral pharmaceutical form FLAMEL TECHNOLOGIES, INC. (FR) 2007-09-27 US claimed
US-20070202049-A1 Oral dosage form comprising an antimisuse system FLAMEL TECHNOLOGIES, INC. (FR) 2007-08-30 US claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007054378-A1 ANTI-MISUSE MICROPARTICULATE ORAL PHARMACEUTICAL FORM FLAMEL TECHNOLOGIES (FR) 2007-05-18 WO claimed
WO-2006134018-A2 ORAL DOSAGE FORM COMPRISING AN ANTIMISUSE SYSTEM FLAMEL TECHNOLOGIES (FR) 2006-12-21 WO claimed
WO-2006133733-A1 ORAL DOSAGE FORM COMPRISING AN ANTIMISUSE SYSTEM FLAMEL TECHNOLOGIES (FR) 2006-12-21 WO claimed
CN-1872063-A Microspheres or composition in use for long acting injection of Nalmefene or its salt, and preparation method TOXICS & MEDICINES INST A M M (CN) 2006-12-06 CN claimed
WO-2006089843-A2 ANTI-MISUSE MICROPARTICULATE ORAL DRUG FORM FLAMEL TECHNOLOGIES (FR) 2006-08-31 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed