Sugi Predict

Sugi Predict / Compounds / SCHEMBL2931119

SCHEMBL2931119

SCHEMBL2931119

Cc1ccc2nc(C)c(C(=O)O)n2c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.54
▸ KDM4E B2RXH2 4/20 0.54
▸ GAA P10253 2/20 0.54
▸ MAPT P10636 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ RAB9A P51151 3/20 0.50
▸ NPC1 O15118 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ POLB P06746 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ KMT2A Q03164 1/20 0.45
▸ COMT P21964 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ EPHB3 P54753 1/20 0.43
▸ MAP3K14 Q99558 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10242673 0.86 KMT2A (0.61) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL3283016 0.85 TGFBR1 (0.55) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL3974420 0.83 ALDH1A1 (0.69) ALDH1A1GAARAB9ANPC1POLB
SCHEMBL21819132 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL12928390 0.83 ALDH1A1 (0.47) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL954716 0.83 EPHB3 (0.57) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL18642162 0.81 RAB9A (0.52) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL10514161 0.81 ALDH1A1 (0.74) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL23092081 0.80 RAB9A (0.45) ALDH1A1KDM4EGAAMAPTHTT
SCHEMBL7820531 0.80 NPC1 (0.72) ALDH1A1KDM4EGAARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 — — EP disclosed
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 — — US disclosed
EP-3856178-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 — — EP disclosed
US-20240327410-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2024-10-03 — — US disclosed
CN-113164458-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-13 — — CN disclosed
CN-113164459-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-09-03 — — CN disclosed
US-20240199651-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-06-20 — — US disclosed
US-20240182495-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-06-06 — — US disclosed
US-11993601-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV 2024-05-28 — — US disclosed
CN-117580843-A Antibacterial compounds 爱尔兰詹森科学公司 2024-02-20 — — CN disclosed
WO-2019175737-A1 DEUTERATED IMIDAZOPYRIDINES UNIVERSITY OF NOTRE DAME DU LAC (US) 2019-09-19 — — WO disclosed
WO-2019175737-A1 DEUTERATED IMIDAZOPYRIDINES UNIVERSITY OF NOTRE DAME DU LAC (US) 2019-09-19 — — WO disclosed
US-20180265506-A1 BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION UNIVERSITY OF NOTRE DAME DU LAC (US) 2018-09-20 — — US disclosed
EP-3328382-A1 BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION Miller, Marvin J. (US) 2018-06-06 — — EP disclosed
WO-2017049321-A1 BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION MILLER MARVIN J (US) 2017-03-23 — — WO disclosed
WO-2017049321-A1 BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION MILLER MARVIN J (US) 2017-03-23 — — WO disclosed
EP-2079690-B1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2010-09-15 — — EP disclosed
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES Actelion Phamaceuticals Ltd. (CH) 2010-01-21 — — US disclosed
EP-2079690-A2 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES Actelion Pharmaceuticals Ltd. (CH) 2009-07-22 — — EP disclosed
WO-2008038251-A2 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2008-04-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199651-A1 ANTIBACTERIAL COMPOUNDS FDPS, MT-ND4, NDUFS3 ALDH1A1 1644/4885KDM4E 3504/4885GAA 424/4885
US-20180265506-A1 BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION BET1, BRD4, BRD3 ALDH1A1 2638/4885KDM4E 2503/4885GAA 917/4885
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH ALDH1A1 587/4885KDM4E 3565/4885GAA 290/4885
US-20240182495-A1 ANTIBACTERIAL COMPOUNDS FDPS, MT-ND4, NDUFS3 ALDH1A1 1644/4885KDM4E 3504/4885GAA 424/4885
US-11993601-B2 Monoacylglycerol lipase modulators MGLL, LPL, PNLIP ALDH1A1 344/4885KDM4E 2800/4885GAA 139/4885
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES HCRTR1, HCRTR2, CNR1 ALDH1A1 702/4885KDM4E 735/4885GAA 3717/4885
US-20240327410-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP ALDH1A1 344/4885KDM4E 2800/4885GAA 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.