Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380616 | 0.76 | LMNA (0.60) | ALDH1A1KDM4EMAPTHPGDTSHR | |
| SCHEMBL27214488 | 0.73 | L3MBTL1 (0.56) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL2722810 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL2912873 | 0.71 | KDM4E (0.73) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL1559086 | 0.70 | HPGD (0.53) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2951611 | 0.70 | HPGD (0.59) | ALDH1A1KDM4EHPGDHSD17B10SIGMAR1 | |
| SCHEMBL3030899 | 0.70 | SIGMAR1 (0.70) | ALDH1A1KDM4EHPGDSIGMAR1TMEM97 | |
| SCHEMBL5535003 | 0.70 | ALDH1A1 (0.55) | POLBALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7620985 | 0.69 | NPC1 (0.57) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL2315291 | 0.69 | HPGD (0.65) | ALDH1A1KDM4EGAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |