Sugi Predict

Sugi Predict / Compounds / SCHEMBL1104855

SCHEMBL1104855

SCHEMBL1104855

Cc1ccc2c(c1)nc(C)n2C

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 10/20 0.59
▸ NPC1 O15118 9/20 0.59
▸ KDM4E B2RXH2 5/20 0.58
▸ ALDH1A1 P00352 3/20 0.58
▸ LMNA P02545 1/20 0.58
▸ MAPT P10636 4/20 0.57
▸ HSD17B10 Q99714 2/20 0.53
▸ ACSS2 Q9NR19 1/20 0.51
▸ KMT2A Q03164 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ HDAC1 Q13547 1/20 0.48
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ HTT P42858 2/20 0.47
▸ POLB P06746 2/20 0.47
▸ TP53 P04637 1/20 0.47
▸ HPGD P15428 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104857 0.83 KDM4E (0.58) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL8112774 0.80 KDM4E (0.55) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL20921174 0.80 KDM4E (0.50) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL297992 0.80 KDM4E (0.60) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL8052547 0.80 RAB9A (0.59) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL958660 0.80 RAB9A (0.58) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL14311763 0.80 KDM4E (0.54) RAB9ANPC1KDM4EMAPTHSD17B10
SCHEMBL2515278 0.80 KDM4E (0.55) RAB9ANPC1KDM4EALDH1A1LMNA
SCHEMBL11823 0.80 TLR8 (0.58) RAB9ANPC1KDM4EALDH1A1MAPT
SCHEMBL435075 0.80 NPC1 (0.61) RAB9ANPC1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0318294-B1 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS (JP) 1994-12-28 — — EP claimed
US-20230234937-A1 INDENOAZANAPHTHALENES MERCK PATENT GMBH (DE) 2023-07-27 — — US disclosed
US-20230234943-A1 TREX1 INHIBITORS AND USES THEREOF TEMPEST THERAPEUTICS, INC. 2023-07-27 — — US disclosed
US-11702409-B2 Pyrazolyl derivatives useful as anti-cancer agents NOVARTIS AG (CH) 2023-07-18 — — US disclosed
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 — — US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 — — US disclosed
EP-3381896-B1 BIPHENYL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2023-01-18 — — EP disclosed
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-12-22 — — US disclosed
WO-2022241956-A1 FLEXIBLE SUBSTRATE AND MANUFACTURING METHOD THEREFOR, AND DISPLAY PANEL 深圳市华星光电半导体显示技术有限公司 2022-11-24 — — WO disclosed
US-11189809-B2 Organic EL device and display unit SONY CORPORATION (JP) 2021-11-30 — — US disclosed
WO-2008117175-A2 NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE ADDEX PHARMA SA (CH) 2008-10-02 — — WO disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 — — US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 — — US disclosed
US-20080114040-A1 Epothilone Derivatives NOVARTIS AG (CH) 2008-05-15 — — US disclosed
US-20080114040-A1 Epothilone Derivatives NOVARTIS AG (CH) 2008-05-15 — — US disclosed
WO-2007109334-A2 SIP RECEPTOR MODULATING COMPOUNDS AND USE THEREOF EPIX DELAWARE, INC. (US) 2007-09-27 — — WO disclosed
EP-1539768-B1 A NEW PROCESS FOR THE PREPARATION OF EPOTHILONE DERIVATIVES NOVARTIS AG (CH) 2007-09-19 — — EP disclosed
EP-0318294-B1 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS (JP) 1994-12-28 — — EP disclosed
US-5125930-A Polymeric cationic dyes including a quaternized pyridinium group NIPPON CHEMICAL WORKS CO., LTD. (JP) 1992-06-30 — — US disclosed
EP-0318294-A2 Dimeric and trimeric cationic dyes NIPPON CHEMICAL WORKS CO., LTD (JP) 1989-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234943-A1 TREX1 INHIBITORS AND USES THEREOF FEN1, ERCC4, DCLRE1B RAB9A 2016/4885NPC1 352/4885KDM4E 2430/4885
US-11702409-B2 Pyrazolyl derivatives useful as anti-cancer agents PAK5, CYP51A1, SF3B5 RAB9A 607/4885NPC1 718/4885KDM4E 2184/4885
US-20080114040-A1 Epothilone Derivatives EPOR, CYP11B2, VKORC1L1 RAB9A 2885/4885NPC1 657/4885KDM4E 3909/4885
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PPOX, EPCAM, STOM RAB9A 1837/4885NPC1 4113/4885KDM4E 2892/4885
US-20230234937-A1 INDENOAZANAPHTHALENES NQO1, CYP2D6, SQOR RAB9A 3684/4885NPC1 2454/4885KDM4E 1585/4885
US-11189809-B2 Organic EL device and display unit L1CAM, ESR1, EPHA8 RAB9A 3991/4885NPC1 1855/4885KDM4E 998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.