Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035772 | 0.82 | ALDH1A1 (0.37) | THRBTSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL1028591 | 0.82 | THRB (0.38) | THRBTSHRALDH1A1HPGDKDM4E | |
| SCHEMBL1038469 | 0.82 | CRHR1 (0.34) | TSHRHPGDCYP3A4KDM4EL3MBTL1 | |
| SCHEMBL2886656 | 0.82 | CRHR1 (0.34) | TSHRHPGDCYP3A4KDM4EL3MBTL1 | |
| SCHEMBL1039014 | 0.81 | NLRP3 (0.44) | TSHRALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL1034149 | 0.81 | HTR1A (0.35) | HPGDKDM4EL3MBTL1MEN1LMNA | |
| SCHEMBL1037680 | 0.81 | HTR1A (0.35) | HPGDKDM4EL3MBTL1MEN1LMNA | |
| SCHEMBL1038151 | 0.81 | HTR1A (0.35) | HPGDKDM4EL3MBTL1MEN1LMNA | |
| SCHEMBL1036934 | 0.80 | KDM4E (0.36) | HPGDKDM4EL3MBTL1MEN1LMNA | |
| SCHEMBL1033698 | 0.80 | TAS1R3 (0.39) | HPGDMEN1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451847-B1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | IGM GROUP B V (NL) | 2021-11-24 | — | — | EP | disclosed |
| US-9120900-B2 | Polymer-bound bisacylphosphine oxides | BASF SE (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20150025169-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2015-01-22 | — | — | US | disclosed |
| US-8883872-B2 | Polymer-bound bisacylphosphine oxides | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2012-06-07 | — | — | US | disclosed |
| EP-2451847-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003772-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | PHOSPHO1, PARG, PEBP1 | THRB 4336/4885TSHR 4599/4885ALDH1A1 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.