Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.62 |
| ▸ | CA4 | P22748 | 7/20 | 0.62 |
| ▸ | CA9 | Q16790 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.57 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18500866 | 0.88 | CA12 (0.62) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13299169 | 0.88 | PTGS2 (0.66) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13318494 | 0.88 | P2RX7 (0.51) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13800457 | 0.82 | TTR (0.67) | CA12CA4CA9CA1CA2 | |
| SCHEMBL6950571 | 0.82 | TTR (0.67) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13911574 | 0.82 | PTGS2 (0.64) | CA12CA4CA9CA1CA2 | |
| SCHEMBL25948151 | 0.81 | PTGS2 (0.63) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13318490 | 0.81 | PTGS2 (0.44) | CA12CA4CA9CA1CA2 | |
| SCHEMBL13299162 | 0.79 | TTR (0.73) | CA12CA4CA9CA1CA2 | |
| SCHEMBL30794451 | 0.79 | PTGS2 (0.48) | CA12CA4CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-9403756-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-02 | — | — | US | disclosed |
| EP-2203411-B1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | UNIV RAMOT (IL) | 2016-01-06 | — | — | EP | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-10-23 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8765815-B2 | N-phenyl anthranilic acid derivatives and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-07-01 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-8278357-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-10-02 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-12 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-03-04 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
| US-7632866-B2 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | RAMOT AT TEL AVIV UNIVERSITY (IL) | 2009-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | CA12 3899/4885CA4 1601/4885CA9 3998/4885 |
| US-20140316008-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | CA12 3899/4885CA4 1601/4885CA9 3998/4885 |
| US-20120178785-A1 | DERIVATIVES OF N-PHENYLANTHRANILIC ACID AND 2-BENZIMIDAZOLONE AS POTASSIUM CHANNEL AND/OR NEURON ACTIVITY MODULATORS | KCNN2, KCNN1, KCNN3 | CA12 4743/4885CA4 3739/4885CA9 4492/4885 |
| US-20100056591-A1 | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators | KCNN2, KCNN1, KCNN3 | CA12 4743/4885CA4 3739/4885CA9 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.