Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032473 | 0.85 | RAB9A (0.48) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL1031707 | 0.77 | POLB (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1030744 | 0.76 | POLB (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1033737 | 0.74 | NPC1 (0.49) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1032566 | 0.72 | AURKA (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1032354 | 0.72 | ALDH1A1 (0.44) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1031541 | 0.70 | RAB9A (0.53) | RAB9ANPC1MEN1KMT2APKM | |
| SCHEMBL1028662 | 0.69 | LMNA (0.48) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1031726 | 0.69 | KDM4E (0.49) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL1748908 | 0.69 | GCGR (0.43) | NPSR1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |