SCHEMBL1738355

SCHEMBL1738355

CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(OCCOC)c2Cl)c1O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
RAB9A P51151 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.33
NR3C1 P04150 5/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HTT P42858 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30042076 0.90 SMN1; SMN2 (0.34) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL1032996 0.90 SMN1; SMN2 (0.34) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL10097307 0.85 NR3C1 (0.31) IRAK4NR3C1
SCHEMBL9382070 0.84 ALKBH1 (0.37) SMN1; SMN2RAB9ALMNA
SCHEMBL7962639 0.84 SMN1; SMN2 (0.39) SMN1; SMN2RAB9ANR3C1LMNAGAA
SCHEMBL9076440 0.84 SMN1; SMN2 (0.35) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL8168637 0.84 GNRHR (0.35) SMN1; SMN2RAB9A
SCHEMBL14719792 0.83 NR3C1 (0.30) NR3C1
SCHEMBL1034518 0.82
SCHEMBL9448454 0.82 SMN1; SMN2 (0.40) SMN1; SMN2RAB9ANR3C1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2326722-B1 HERBICIDE TOLERANT PLANTS SYNGENTA LTD (GB) 2014-08-06 EP claimed
US-20110173718-A1 HERBICIDE TOLERANT PLANTS SYNGENTA CROP PROTECTION, INC. (US) 2011-07-14 US claimed
EP-2326722-A2 HERBICIDE TOLERANT PLANTS Syngenta Limited (GB) 2011-06-01 EP claimed
WO-2010029311-A2 HERBICIDE TOLERANT PLANTS SYNGENTA LIMITED (GB) 2010-03-18 WO claimed
JP-2288866-A None JP disclosed
US-20250351828-A1 AZOLE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2025-11-20 US disclosed
EP-4531566-A1 AZOLE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2025-04-09 EP disclosed
US-12065654-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2024-08-20 US disclosed
US-20240090504-A1 DITHIOCARBAMATE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2024-03-21 US disclosed
US-20240023557-A1 COPPER-BASED FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2024-01-25 US disclosed
US-20230413808-A1 Bioactive complexes CERADIS PATENT B.V. (NL) 2023-12-28 US disclosed
WO-2023233378-A1 AZOLE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2023-12-07 WO disclosed
CN-1224419-A Process for preparing 1-alkyl-4-(2-chloro-3-alkoxy-4-alkylsulfonylbenzoyl)-5-hydroxypyrazole and related compounds DOW AGROSCIENCES LLC (US) 1999-07-28 CN disclosed
EP-0928288-A1 PROCESS FOR PREPARING 1-ALKYL-4- (2-CHLORO-3-ALKOXY-4-ALKYLSULFONYLBENZOYL) -5-HYDROXYPYRAZOLE AND RELATED COMPOUNDS Dow AgroSciences LLC (US) 1999-07-14 EP disclosed
WO-1998042677-A1 PROCESS FOR PREPARING 1-ALKYL-4- (2-CHLORO-3-ALKOXY-4-ALKYLSULFONYLBENZOYL) -5-HYDROXYPYRAZOLE AND RELATED COMPOUNDS DOW AGROSCIENCES LLC (US) 1998-10-01 WO disclosed
US-RE34779-E Selective weed control at low dosage without adversely affecting crops NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-11-08 US disclosed
EP-0352543-B1 Pyrazole derivatives and herbicides containing them NISSAN CHEMICAL IND LTD (JP) 1994-09-28 EP disclosed
US-4986845-A PRE-AND POSTEMERGENCE NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-01-22 US disclosed
JP-H02288866-A PYRAZOLE DERIVATIVE AND SELECTIVE HERBICIDE NISSAN CHEM IND LTD 1990-11-28 JP disclosed
EP-0352543-A1 Pyrazole derivatives and herbicides containing them NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-01-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250351828-A1 AZOLE FUNGICIDE COMPOSITION TST, PIK3C3, TPMT SMN1; SMN2 4273/4885RAB9A 4421/4885IRAK4 2883/4885
US-12065654-B2 Plants having increased tolerance to herbicides HPD, MPST, DNTT SMN1; SMN2 3377/4885RAB9A 4530/4885IRAK4 3496/4885
US-20110173718-A1 HERBICIDE TOLERANT PLANTS HPD, LCT, GNPAT SMN1; SMN2 4292/4885RAB9A 4244/4885IRAK4 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.