Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1022542 | 0.96 | FABP4 (0.44) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL1021278 | 0.96 | FABP4 (0.44) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL346543 | 0.96 | FABP4 (0.44) | FABP4FABP3FABP5GABRA1GABRB2 | |
| Sulfurous Acid SCHEMBL30356309 | 0.79 | FABP4 (0.44) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL345363 | 0.77 | FABP4 (0.50) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL1022543 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL1033044 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL1021280 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5GABRA1GABRB2 | |
| Calcium SCHEMBL29853758 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL346544 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12478562-B2 | Dental restoration material composition | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-25 | — | — | US | disclosed |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-11 | — | — | US | disclosed |
| EP-4613256-A1 | DENTAL ADHESIVE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2025-09-10 | — | — | EP | disclosed |
| US-20250213434-A1 | DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY | KURARAY NORITAKE DENTAL INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| WO-2025126917-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2025-06-19 | — | — | WO | disclosed |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | KURARAY NORITAKE DENTAL INC. (JP) | 2025-02-27 | — | — | US | disclosed |
| US-20250057732-A1 | DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2025-02-20 | — | — | US | disclosed |
| US-20250057733-A1 | CURABLE DENTAL COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2025-02-20 | — | — | US | disclosed |
| WO-2025033522-A1 | CURABLE COMPOSITION FOR DENTAL USE | クラレノリタケデンタル株式会社 | 2025-02-13 | — | — | WO | disclosed |
| US-20100048761-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100036075-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2133368-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-2112177-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2112178-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | Kuraray Medical Inc. (JP) | 2009-10-28 | — | — | EP | disclosed |
| EP-2108663-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| EP-2108664-A1 | COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| US-5486544-A | AROMATIC SULFINATE POLYMERIZATION CATALYST | KURARAY CO., LTD. (JP) | 1996-01-23 | — | — | US | disclosed |
| EP-0408357-B1 | Polymerizable composition | KURARAY CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0408357-A2 | Polymerizable composition | KURARAY CO., LTD. (JP) | 1991-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048761-A1 | POLYMERIZABLE MONOMER-CONTAINING COMPOSITION | WDR82, PWWP2B, WDR5 | FABP4 2728/4885FABP3 4604/4885FABP5 2923/4885 |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | BRD1, TBCA, BAZ1A | FABP4 2338/4885FABP3 4208/4885FABP5 2915/4885 |
| US-20250064687-A1 | DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER | MGMT, SEM1, CARM1 | FABP4 4594/4885FABP3 4648/4885FABP5 4625/4885 |
| US-12478562-B2 | Dental restoration material composition | CAD, MAT2B, RER1 | FABP4 3087/4885FABP3 4243/4885FABP5 3635/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | FABP4 4707/4885FABP3 4366/4885FABP5 4441/4885 |
| US-20250057732-A1 | DENTAL CURABLE COMPOSITION | CAD, MMAB, DNMT3L | FABP4 4608/4885FABP3 4857/4885FABP5 4687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.