SCHEMBL1021280

SCHEMBL1021280

CC(C)c1cc(C(C)C)c(S(=O)O)c(C(C)C)c1.[CaH2]

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 3/20 0.48
FABP3 P05413 2/20 0.48
FABP5 Q01469 1/20 0.47
GABRA1 P14867 4/20 0.45
GABRB2 P47870 2/20 0.45
SOAT2 O75908 1/20 0.33
MYC P01106 1/20 0.33
SOAT1 P35610 1/20 0.33
MAP2K3 P46734 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 3/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
GABRB1 P18505 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345363 0.98 FABP4 (0.50) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL1022543 0.96 FABP4 (0.48) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL1033044 0.96 FABP4 (0.48) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL346544 0.96 FABP4 (0.48) FABP4FABP3FABP5GABRA1GABRB2
Calcium SCHEMBL29853758 0.96 FABP4 (0.48) FABP4FABP3FABP5GABRA1GABRB2
Sulfurous Acid SCHEMBL30356309 0.90 FABP4 (0.44) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL8958889 0.77 GABRA1 (0.48) GABRA1GABRB2CA1CA2ALDH1A1
SCHEMBL15741262 0.77 FABP4 (0.50) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL13970208 0.76 GSR (0.35) CA1CA2
SCHEMBL1021278 0.75 FABP4 (0.44) FABP4FABP3FABP5GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
EP-4613256-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-09-10 EP disclosed
US-12396929-B2 Dental composition DENTSPLY SIRONA INC. (US) 2025-08-26 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
US-20250082550-A1 BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS DENTSPLY SIRONA INC. (US) 2025-03-13 US disclosed
US-20250064687-A1 DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER KURARAY NORITAKE DENTAL INC. (JP) 2025-02-27 US disclosed
US-20250057732-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
CN-1703185-A Dental coating kit KURARAY MEDICAL INC (JP) 2005-11-30 CN disclosed
US-6939901-B2 Adhesive composition KURARAY MEDICAL, INC. (JP) 2005-09-06 US disclosed
EP-1550428-A1 DENTAL COATING KIT Kuraray Medical Inc. (JP) 2005-07-06 EP disclosed
CN-1152661-C Cementation composite and prepn. method therefor �����ɷ� 2004-06-09 CN disclosed
US-6512068-B1 Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of KURARAY CO., LTD. (JP) 2003-01-28 US disclosed
US-20020198284-A1 Adhesive composition KURARAY CO. LTD, (JP) 2002-12-26 US disclosed
EP-1262530-A1 ADHESIVE COMPOSITION KURARAY CO., LTD. (JP) 2002-12-04 EP disclosed
CN-1277834-A Cementation composite and prepn. method therefor KURARAY CO (JP) 2000-12-27 CN disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed
CN-1253767-A Adhesive compound for tooth KURARAY CO (JP) 2000-05-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12396929-B2 Dental composition CAD, PHOSPHO1, PLA2G2C FABP4 2856/4885FABP3 4061/4885FABP5 3953/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A FABP4 2338/4885FABP3 4208/4885FABP5 2915/4885
US-20250064687-A1 DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER MGMT, SEM1, CARM1 FABP4 4594/4885FABP3 4648/4885FABP5 4625/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 FABP4 3087/4885FABP3 4243/4885FABP5 3635/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL FABP4 4707/4885FABP3 4366/4885FABP5 4441/4885
US-20250057732-A1 DENTAL CURABLE COMPOSITION CAD, MMAB, DNMT3L FABP4 4608/4885FABP3 4857/4885FABP5 4687/4885
US-20250082550-A1 BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS DUOX2, DUOX1, QSOX1 FABP4 4079/4885FABP3 4635/4885FABP5 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.