SCHEMBL10331647

SCHEMBL10331647

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)ccc4n5-c4cccc(-n5c6ccccc6c6ccccc65)c4)ccc32)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.64
▸ KDM4E B2RXH2 2/20 0.64
▸ ATM Q13315 1/20 0.64
▸ KMT2A Q03164 3/20 0.41
▸ IL1R1 P14778 1/20 0.41
▸ PTGER4 P35408 1/20 0.40
▸ TSPO P30536 1/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ EDNRB P24530 1/20 0.37
▸ EDNRA P25101 1/20 0.37
▸ MAPK8 P45983 2/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ PGR P06401 1/20 0.37
▸ MAPK9 P45984 1/20 0.36
▸ KDR P35968 1/20 0.36
▸ FOLH1 Q04609 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10042633 1.00 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15435799 1.00 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL14649303 0.97 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL26624906 0.97 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18352325 0.96 KDM4E (0.57) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18352545 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15435970 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15435798 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15435968 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15435963 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 — — US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 — — US disclosed
US-9386657-B2 Organic Electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-05 — — US disclosed
US-9386657-B2 Organic Electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-05 — — US disclosed
US-9382206-B2 Nitrogen-containing aromatic heterocyclic derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-07-05 — — US disclosed
US-9382206-B2 Nitrogen-containing aromatic heterocyclic derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-07-05 — — US disclosed
US-20130241400-A1 SECONDARY HOLE TRANSPORTING LAYER WITH TRICARBAZOLE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2013-09-19 — — US disclosed
US-20130241400-A1 SECONDARY HOLE TRANSPORTING LAYER WITH TRICARBAZOLE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2013-09-19 — — US disclosed
US-20120181524-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 — — US disclosed
US-20120181524-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 L3MBTL1 1678/4885KDM4E 3248/4885ATM 2324/4885
US-20120181524-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME AOC3, NPR3, NR0B1 L3MBTL1 4455/4885KDM4E 3595/4885ATM 2952/4885
US-20130241400-A1 SECONDARY HOLE TRANSPORTING LAYER WITH TRICARBAZOLE COMPOUNDS SLC25A1, ABCG2, SLC43A1 L3MBTL1 466/4885KDM4E 3261/4885ATM 3366/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 L3MBTL1 1678/4885KDM4E 3248/4885ATM 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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