SCHEMBL28114764

SCHEMBL28114764

CCc1nn(-c2ccc(CCl)cc2)c(=O)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
ATM Q13315 1/20 0.35
MGLL Q99685 1/20 0.33
ADORA3 P0DMS8 3/20 0.33
HCAR1 Q9BXC0 2/20 0.33
NPBWR1 P48145 2/20 0.32
MCHR1 Q99705 2/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
GLA P06280 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10338166 0.84 KMT2A (0.42) L3MBTL1MEN1KMT2APOLBADORA3
SCHEMBL10274594 0.81 ADORA3 (0.47) L3MBTL1POLBADORA3HPGDKDM4E
SCHEMBL9779799 0.68 ALDH1A1 (0.33) L3MBTL1MEN1KMT2A
SCHEMBL9033166 0.67 PARP1 (0.48) L3MBTL1ADORA3HCAR1HPGDKDM4E
SCHEMBL28114801 0.67 TDP1 (0.40) L3MBTL1MEN1KMT2APOLBMGLL
SCHEMBL7067294 0.62 GAA (0.47) L3MBTL1MEN1KMT2APOLBADORA3
SCHEMBL16285366 0.61 MGLL (0.44) POLBMGLLADORA3HCAR1NPBWR1
SCHEMBL52437 0.61 TP53 (0.50) L3MBTL1POLBATMMGLLTSHR
SCHEMBL21371452 0.59 MEN1 (0.34) MEN1KMT2AGLA
SCHEMBL7801043 0.59 TP53 (0.48) L3MBTL1POLBATMMGLLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496275-B Silty soil roadbed solidifying agent and preparation method thereof 山西省交通科学研究院 2017-01-11 CN disclosed