SCHEMBL1034075

SCHEMBL1034075

CNc1nc(-c2ccccc2)nc(N(C)C)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 2/20 0.49
OPRM1 P35372 1/20 0.47
OPRL1 P41146 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
IMPDH2 P12268 1/20 0.44
NUDT1 P36639 2/20 0.44
TSHR P16473 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28184867 0.83 ALDH1A1 (0.75) ALDH1A1MEN1KMT2AIMPDH2TSHR
SCHEMBL24218050 0.83 TDP1 (0.61) ALDH1A1TDP1MEN1KMT2ANUDT1
SCHEMBL1030285 0.83 TDP1 (0.61) TDP1MEN1KMT2AIMPDH2NUDT1
SCHEMBL14274943 0.83 MEN1 (0.55) ALDH1A1OPRM1OPRL1MEN1KMT2A
SCHEMBL6978463 0.80 TDP1 (0.57) TDP1MEN1KMT2AIMPDH2NUDT1
SCHEMBL22435819 0.77 L3MBTL1 (0.67) ALDH1A1TDP1MEN1KMT2ANUDT1
SCHEMBL26793554 0.77 L3MBTL1 (0.67) ALDH1A1MEN1KMT2ANUDT1TSHR
SCHEMBL19295118 0.75 MEN1 (0.47) ALDH1A1TDP1MEN1KMT2ANUDT1
SCHEMBL527618 0.75 ADORA2A (0.64) ALDH1A1TDP1MEN1KMT2ANUDT1
SCHEMBL7608701 0.75 SMN1; SMN2 (0.69) MEN1KMT2ANUDT1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11029615-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-06-08 US disclosed
US-10935898-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-03-02 US disclosed
US-20210033991-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-02-04 US disclosed
US-20200124996-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-04-23 US disclosed
US-10031394-B2 Electrophoretic particle, electrophoretic particle dispersion liquid, display medium, and display device E INK CORPORATION (US) 2018-07-24 US disclosed
EP-2268610-B1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP BOREALIS AGROLINZ MELAMINE (AT) 2016-08-03 EP disclosed
US-8871842-B2 Method for producing a compound with at least one at least monosubstituted amino group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2014-10-28 US disclosed
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2011-07-21 US disclosed
EP-2268610-A1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP Borealis Agrolinz Melamine GmbH (AT) 2011-01-05 EP disclosed
WO-2009121603-A1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP BOREALIS AGROLINZ MELAMINE GMBH (AT) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group INMT, AADAT, AANAT ALDH1A1 133/4885TDP1 3692/4885OPRM1 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.