Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | POLB | P06746 | 6/20 | 0.67 |
| ▸ | MMP13 | P45452 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL10351431 | 1.00 | MEN1 (0.73) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL6264761 | 0.88 | MEN1 (0.81) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL11207327 | 0.88 | MEN1 (0.81) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL10713249 | 0.87 | MEN1 (0.79) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL7019338 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL10036060 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL8887899 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL10661708 | 0.81 | MEN1 (0.76) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL9858108 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBMMP13 | |
| SCHEMBL9858105 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185100-B1 | PROCESS FOR PREPARING SILVER HALIDE EMULSION | FUJI PHOTO FILM CO LTD (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4713321-A | SENSITIZING DYES, OXIDIZERS SUCH AS PEROXIDES | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| EP-0185100-A1 | PROCESS FOR PREPARING SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-25 | — | — | EP | disclosed |