SCHEMBL1037240

SCHEMBL1037240

Cc1cc(C)c(C(=O)P(=O)(CC(=O)CC(=O)OC(C)C)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.37
TSHR P16473 5/20 0.37
KDM4E B2RXH2 5/20 0.37
ALDH1A1 P00352 5/20 0.34
ALOX15 P16050 1/20 0.34
LMNA P02545 2/20 0.33
CISD2 Q8N5K1 1/20 0.32
TAS1R3 Q7RTX0 3/20 0.32
TAS1R1 Q7RTX1 3/20 0.32
TAS1R2 Q8TE23 3/20 0.32
HPGD P15428 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GAA P10253 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033908 0.86 TAS1R3 (0.35) HSD17B10KDM4EALDH1A1LMNATAS1R3
SCHEMBL1035049 0.83 NLRP3 (0.43) HSD17B10KDM4EALDH1A1LMNATAS1R3
SCHEMBL1035650 0.80 TAS1R3 (0.36) KDM4EALDH1A1LMNATAS1R3TAS1R1
SCHEMBL1030595 0.78 POLB (0.40) KDM4ELMNATAS1R3TAS1R1TAS1R2
SCHEMBL1038734 0.76 FAAH (0.47) TSHRNPSR1
SCHEMBL1037378 0.75 TSHR (0.37) TSHRKDM4EALDH1A1ALOX15LMNA
SCHEMBL24498757 0.75 HPGD (0.33) TSHRKDM4ELMNACISD2TAS1R3
SCHEMBL1039014 0.74 NLRP3 (0.44) HSD17B10TSHRKDM4EALDH1A1LMNA
SCHEMBL1038296 0.73 KMT2A (0.47) KDM4EALDH1A1ALOX15LMNAHPGD
SCHEMBL27489123 0.73 TAS1R3 (0.41) HSD17B10TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814891-B1 BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES BASF SE (DE) 2011-01-26 EP disclosed
US-7687657-B2 Process for preparing acylphosphanes and derivatives thereof CIBA SPECIALITY CHEMICALS CORPORATION (US) 2010-03-30 US disclosed
US-20080004464-A1 Process for Preparing Acylphosphanes and Derivatives Thereof IGM GROUP B.V. (NL) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004464-A1 Process for Preparing Acylphosphanes and Derivatives Thereof ME2, ME3, MEP1A HSD17B10 1078/4885TSHR 1504/4885KDM4E 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.