SCHEMBL1035650

SCHEMBL1035650

CC(=O)CC(=O)CP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 4/20 0.36
TAS1R1 Q7RTX1 4/20 0.36
TAS1R2 Q8TE23 4/20 0.36
LMNA P02545 4/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1033908 0.84 TAS1R3 (0.35) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL1035049 0.82 NLRP3 (0.43) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL1037240 0.80 HSD17B10 (0.37) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL1038296 0.80 KMT2A (0.47) LMNAKMT2AMEN1SMN1; SMN2HPGD
SCHEMBL1032446 0.80 GAA (0.42) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL12956793 0.79 L3MBTL1 (0.39) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL1030595 0.79 POLB (0.40) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL2710988 0.78 GAA (0.41) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL1033218 0.78 LMNA (0.38) TAS1R3TAS1R1TAS1R2LMNAKMT2A
SCHEMBL691620 0.77 LMNA (0.37) TAS1R3TAS1R1TAS1R2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814891-B1 BISACYLPHOSPHANES AND THEIR USE AS PHOTOINITIATORS; PROCESS FOR PREPARING ACYLPHOSPHANES BASF SE (DE) 2011-01-26 EP disclosed
US-7687657-B2 Process for preparing acylphosphanes and derivatives thereof CIBA SPECIALITY CHEMICALS CORPORATION (US) 2010-03-30 US disclosed
US-20080004464-A1 Process for Preparing Acylphosphanes and Derivatives Thereof IGM GROUP B.V. (NL) 2008-01-03 US disclosed
EP-1814891-A1 PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF Ciba Specialty Chemicals Holding Inc. (CH) 2007-08-08 EP disclosed
WO-2006056541-A1 PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004464-A1 Process for Preparing Acylphosphanes and Derivatives Thereof ME2, ME3, MEP1A TAS1R3 1630/4885TAS1R1 2270/4885TAS1R2 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.