SCHEMBL10396190

SCHEMBL10396190

C=C(F)C(=O)OC(c1ccc(C(OC(=O)C(=C)F)(C(F)(F)F)C(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
NPSR1 Q6W5P4 3/20 0.38
MAPT P10636 2/20 0.38
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ATM Q13315 1/20 0.32
RORC P51449 2/20 0.32
EPHX2 P34913 1/20 0.31
ALDH1A1 P00352 1/20 0.30
PGK1 P00558 1/20 0.30
PGK2 P07205 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
MLYCD O95822 1/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
KIF11 P52732 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418936 0.93 RORC (0.39) LMNANPSR1MAPTCES2CES1
SCHEMBL9418917 0.91 CA1 (0.36) LMNANPSR1MAPTCES2CES1
SCHEMBL9418908 0.85 PPARD (0.32) LMNANPSR1MAPTCES2CES1
SCHEMBL10396191 0.85 NPSR1 (0.37) LMNANPSR1MAPTCES2CES1
SCHEMBL24908565 0.79 ESR1 (0.40) LMNANPSR1MAPTALDH1A1ESR1
SCHEMBL7084775 0.79 RORC (0.38) LMNANPSR1MAPTMEN1KMT2A
SCHEMBL15840364 0.78 SMN1; SMN2 (0.47) LMNANPSR1MLYCDSMN1; SMN2
SCHEMBL21834941 0.77 MAPT (0.40) LMNANPSR1MAPTCES1MEN1
SCHEMBL3692621 0.77 ELANE (0.41) LMNANPSR1MAPTCES1MEN1
SCHEMBL27218966 0.76 HSD11B1 (0.40) LMNAMAPTCES2CES1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4910275-A Copolymer of an acrylated polyether and an acrylated ester DAIKIN INDUSTRIES, LTD. (JP) 1990-03-20 US disclosed
EP-0305954-A1 Dental material DAIKIN INDUSTRIES, LIMITED (JP) 1989-03-08 EP disclosed