SCHEMBL1040119

SCHEMBL1040119

Cc1ccc(-c2cccc(N)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.67
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
MAP4K4 O95819 4/20 0.52
KDM4E B2RXH2 4/20 0.50
NPC1 O15118 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPT P10636 4/20 0.50
RAB9A P51151 4/20 0.50
CYP3A4 P08684 3/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 3/20 0.50
CYP17A1 P05093 2/20 0.50
CYP19A1 P11511 2/20 0.50
CYP11B1 P15538 2/20 0.50
CYP11B2 P19099 2/20 0.50
GFER P55789 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23542887 1.00 MAOA (0.67) MAOACA12CA1CA2CA9
SCHEMBL19901315 0.89 MAOA (0.64) MAOACA12CA1CA2CA9
SCHEMBL19446666 0.88 MAOA (0.84) MAOACA12CA1CA2CA9
SCHEMBL29561461 0.88 MAOA (0.84) MAOACA12CA1CA2CA9
SCHEMBL311194 0.88 MAOA (0.84) MAOACA12CA1CA2CA9
SCHEMBL31131353 0.88 MAOA (0.84) MAOACA12CA1CA2CA9
SCHEMBL29394565 0.88 MAOA (0.84) MAOACA12CA1CA2CA9
SCHEMBL13448183 0.87 MAOA (0.61) MAOACA12CA1CA2CA9
SCHEMBL13448362 0.87 MAOA (0.61) MAOACA12CA1CA2CA9
SCHEMBL18960511 0.86 ACHE (0.59) MAOACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150141642-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2015-05-21 US claimed
EP-2862913-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2015-04-22 EP claimed
EP-1919875-A2 PYRAZOLE DERIVATIVES AND THEIR USE AS PKA AND PKB MODULATORS Astex Therapeutics Limited (GB) 2008-05-14 EP claimed
WO-2006136829-A2 PYRAZOLE DERIVATIVES AND THEIR USE AS PKA AND PKB MODULATORS ASTEX THERAPEUTICS LIMITED (GB) 2006-12-28 WO claimed
US-20060276453-A1 Anti-Cytokine Heterocyclic Compounds BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2006-12-07 US claimed
EP-4395500-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4395497-A1 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4395521-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE COMPRISING THE CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS COMPRISING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
WO-2024117859-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-06-06 WO disclosed
EP-4306612-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2024-01-17 EP disclosed
WO-2023235380-A1 MACROLIDES FOR TREATING GENETIC DISEASES ZIKANI THERAPEUTICS, INC. (US) 2023-12-07 WO disclosed
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20070112034-A1 2-(benzimidazol-1-yl)-acetamide bisaryl derivatives AKZO NOBEL N.V. (NL) 2007-05-17 US disclosed
WO-2006136829-A2 PYRAZOLE DERIVATIVES AND THEIR USE AS PKA AND PKB MODULATORS ASTEX THERAPEUTICS LIMITED (GB) 2006-12-28 WO disclosed
US-20060276453-A1 Anti-Cytokine Heterocyclic Compounds BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2006-12-07 US disclosed
WO-2006052499-A1 CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS ARRAY BIOPHARMA, INC. (US) 2006-05-18 WO disclosed
US-20060094644-A1 Capreomycin derivatives and their use as antibacterials ARRAY BIOPHARMA, INC. 2006-05-04 US disclosed
US-20050238917-A1 Charge transporting polymer and production process thereof, and polymer composition for organic electroluminescence device and organic electroluminescence device JSR CORPORATION (JP) 2005-10-27 US disclosed
EP-1589595-A2 Charge transporting polymer and production process thereof, and polymer composition for organic electroluminescence device and organic electroluminescence device JSR Corporation (JP) 2005-10-26 EP disclosed
CN-1033584-C Benzo-fused lactams that promote release of growth hormone MERCK & CO INC (US) 1996-12-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, FOXM1 MAOA 1432/4885CA12 2600/4885CA1 2274/4885
US-20060094644-A1 Capreomycin derivatives and their use as antibacterials SPOUT1, CAPRIN1, FBL MAOA 1940/4885CA12 4390/4885CA1 4584/4885
US-20070112034-A1 2-(benzimidazol-1-yl)-acetamide bisaryl derivatives TRPV1, TRPV3, TRPV2 MAOA 1543/4885CA12 1564/4885CA1 1203/4885
US-20060276453-A1 Anti-Cytokine Heterocyclic Compounds MAPKAPK2, MAP4K2, MAP3K2 MAOA 2618/4885CA12 3780/4885CA1 3255/4885
US-20150141642-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, RPLP0 MAOA 604/4885CA12 2331/4885CA1 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.