Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413339 | 0.94 | DRD2 (0.45) | SIGMAR1BCHEACHEDRD2DRD3 | |
| SCHEMBL10412992 | 0.89 | SLC18A3 (0.47) | SIGMAR1BCHEACHEDRD2DRD3 | |
| SCHEMBL10650004 | 0.88 | DRD2 (0.47) | SIGMAR1BCHEACHEHTR1ADRD2 | |
| SCHEMBL10413746 | 0.87 | HTR1A (0.48) | SIGMAR1BCHEACHEHTR1ADRD2 | |
| SCHEMBL10412980 | 0.87 | HTR1D (0.47) | SIGMAR1BCHEACHEHTR1ADRD2 | |
| SCHEMBL10414153 | 0.86 | DRD2 (0.43) | SIGMAR1BCHEACHEHTR1ADRD2 | |
| SCHEMBL10414224 | 0.85 | SIGMAR1 (0.46) | SIGMAR1BCHEACHEHTR1ASLC6A4 | |
| SCHEMBL10412925 | 0.84 | DRD2 (0.41) | SIGMAR1BCHEACHEDRD2DRD3 | |
| SCHEMBL10650001 | 0.84 | DRD2 (0.49) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL10413272 | 0.83 | HTR1A (0.51) | SIGMAR1BCHEACHEHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |