Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.38 |
| ▸ | RXRA | P19793 | 8/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 2/20 | 0.35 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417635 | 0.81 | KIF11 (0.60) | KIF11KDM4E | |
| SCHEMBL10417304 | 0.75 | LMNA (0.45) | ABCB11HDAC6ELOVL1PIM1KDM4E | |
| SCHEMBL28733754 | 0.74 | KIF11 (0.50) | KIF11ABCB11HDAC6 | |
| SCHEMBL15885350 | 0.68 | NAMPT (0.43) | KIF11PIM1 | |
| SCHEMBL10417180 | 0.67 | ABCB11 (0.74) | ABCB11HDAC6ELOVL1KDM4E | |
| SCHEMBL31013382 | 0.67 | KIF11 (0.47) | KIF11 | |
| SCHEMBL10417591 | 0.67 | ABCB11 (0.71) | ABCB11HDAC6ELOVL1KDM4E | |
| SCHEMBL10417190 | 0.66 | ALDH1A1 (0.55) | ABCB11HDAC6ELOVL1 | |
| SCHEMBL10371527 | 0.66 | ADRA2A (0.35) | KIF11ABCB11HDAC6PIM1KDR | |
| SCHEMBL1505919 | 0.65 | ABCB11 (0.60) | ABCB11HDAC6ELOVL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178035-B1 | ANTI-INFLAMMATORY 1,N-DIARYLPYRAZOL-3-AMINES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | FISONS plc (GB) | 1990-01-03 | — | — | EP | claimed |