Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 12/20 | 0.45 |
| ▸ | PYGL | P06737 | 11/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424875 | 0.91 | PYGM (0.46) | PYGMPYGLTSHRHSD17B10ADORA2B | |
| SCHEMBL10426101 | 0.87 | ADORA2B (0.42) | PYGMPYGLKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9828735 | 0.86 | KDM4E (0.36) | PYGMPYGLKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10425160 | 0.85 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL9864934 | 0.83 | PYGM (0.49) | PYGMPYGLGAATSHRADORA2B | |
| SCHEMBL30157261 | 0.80 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL4072118 | 0.80 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL9865794 | 0.78 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL9828158 | 0.78 | PYGM (0.35) | PYGMPYGL | |
| SCHEMBL10424603 | 0.77 | HSD17B10 (0.56) | KDM4ECYP1A2CYP3A4GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801715-A | HYPOGLYCEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | claimed |
| US-4894378-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-16 | — | — | US | disclosed |
| US-4801715-A | HYPOGLYCEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | disclosed |