Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 16/20 | 0.49 |
| ▸ | PYGL | P06737 | 15/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072118 | 0.90 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL30157261 | 0.90 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL9865794 | 0.88 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL10968852 | 0.85 | PYGM (0.37) | PYGMPYGLGAATSHRALDH1A1 | |
| SCHEMBL10425160 | 0.84 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL10425201 | 0.83 | PYGM (0.45) | PYGMPYGLGAATSHRADORA2B | |
| SCHEMBL9865950 | 0.81 | PYGM (0.52) | PYGMPYGL | |
| SCHEMBL10424875 | 0.80 | PYGM (0.46) | PYGMPYGLTSHRADORA2B | |
| SCHEMBL10660400 | 0.80 | PYGM (0.49) | PYGMPYGLGAATSHRADORA2B | |
| SCHEMBL9867642 | 0.79 | PYGL (0.46) | PYGMPYGLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026714-A | Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabetics | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-25 | — | — | US | claimed |