Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 15/20 | 0.46 |
| ▸ | PYGL | P06737 | 14/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864934 | 0.88 | PYGM (0.49) | PYGMPYGLADORA2B | |
| SCHEMBL10969370 | 0.87 | PYGM (0.35) | PYGMPYGLNR3C2 | |
| SCHEMBL30157261 | 0.86 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL4072118 | 0.86 | PYGM (0.62) | PYGMPYGL | |
| SCHEMBL10425160 | 0.80 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL10425201 | 0.78 | PYGM (0.45) | PYGMPYGLADORA2B | |
| SCHEMBL9865950 | 0.78 | PYGM (0.52) | PYGMPYGL | |
| SCHEMBL10424875 | 0.76 | PYGM (0.46) | PYGMPYGLADORA2B | |
| SCHEMBL9865516 | 0.75 | PYGL (0.48) | PYGMPYGLLMNA | |
| SCHEMBL10968852 | 0.74 | PYGM (0.37) | PYGMPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026714-A | Novel 1-alkyl-substituted 1,4-dihydropyridinelactone anti-diabetics | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-25 | — | — | US | claimed |