Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.39 |
| ▸ | BCHE | P06276 | 8/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434591 | 0.84 | PDCD1 (0.34) | KDM4ENPC1ALDH1A1GAAMAPT | |
| SCHEMBL8316269 | 0.80 | ACHE (0.39) | ACHEBCHEGRIN1GRIN2ATYMS | |
| Hydrochloric Acid SCHEMBL8313444 | 0.80 | ALDH1A1 (0.39) | ACHEBCHEGRIN1GRIN2AKDM4E | |
| SCHEMBL8315862 | 0.79 | ALOX5 (0.44) | KDM4ENPC1ALDH1A1GAAMAPT | |
| SCHEMBL8314378 | 0.79 | RAB9A (0.40) | ACHEBCHEGRIN1GRIN2AKDM4E | |
| Hydrochloric Acid SCHEMBL8315136 | 0.78 | ACHE (0.36) | ACHEBCHEGRIN1GRIN2AKDM4E | |
| Hydrochloric Acid SCHEMBL8311899 | 0.78 | RAB9A (0.39) | ACHEBCHEGRIN1GRIN2AKDM4E | |
| Hydrochloric Acid SCHEMBL8313470 | 0.77 | ACHE (0.40) | ACHEBCHEGRIN1GRIN2ATYMS | |
| SCHEMBL8314532 | 0.76 | RAB9A (0.40) | ACHEBCHEGRIN1GRIN2AKDM4E | |
| Hydrochloric Acid SCHEMBL8315904 | 0.75 | ACHE (0.39) | ACHEBCHEGRIN1GRIN2ATYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |