SCHEMBL1044609

SCHEMBL1044609

CC(N)C1=CC(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28287132 0.98 GABRP (0.32) GABRPGABRDGABRA1GABRB1GABRG2
Ammonia Solution, Strong SCHEMBL27921266 0.79 EEF2K (0.37)
SCHEMBL18774938 0.78 TAAR1 (0.32)
SCHEMBL331189 0.77
SCHEMBL31374862 0.77
SCHEMBL1887395 0.77
SCHEMBL29191349 0.74
SCHEMBL181553 0.74
SCHEMBL8733040 0.74
SCHEMBL752841 0.74 HDAC4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-03-10 US claimed
CN-111514286-B Zika virus E protein conjugate vaccine and preparation method thereof 中国科学院过程工程研究所 2022-03-08 CN claimed
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-07-29 US claimed
EP-3703666-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS Universidade de Santiago de Compostela (ES) 2020-09-09 EP claimed
CN-109651224-A A kind of fluorescence protein crosslinking agent and preparation method thereof 苏州昊帆生物股份有限公司 2019-04-19 CN claimed
US-20260102500-A1 PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH POLYMETHINE DYE TARGETING SMARTDYELIVERY GMBH (DE) 2026-04-16 US disclosed
EP-4720089-A1 COMPOSITIONS AND METHODS FOR IMAGING AND TREATING ENDOMETRIOSIS Endomet Biosciences, Inc. (US) 2026-04-08 EP disclosed
US-20250354056-A1 POLYMER DOTS BIO RAD LABORATORIES INC (US) 2025-11-20 US disclosed
US-12472259-B2 PKC inhibitors for the treatment of septic cholestasis with polymethine dye targeting SMARTDYELIVERY GMBH (DE) 2025-11-18 US disclosed
EP-4638489-A1 PROTEIN-BASED CONJUGATION CARRIERS Ablynx N.V. (BE) 2025-10-29 EP disclosed
EP-4601648-A2 ACRIDINIUM COMPOUNDS WITH FUSED HETEROCYCLES Siemens Healthcare Diagnostics Inc. (US) 2025-08-20 EP disclosed
EP-3962491-B1 INTRACELLULAR DELIVERY OF ANTI-KRAS ANTIBODIES FORMULATED INTO NANOCAPSULES UNIV SANTIAGO COMPOSTELA (ES) 2025-08-06 EP disclosed
WO-2006124737-A2 MOLECULAR CONSTRUCTS SUITABLE FOR TARGETED CONJUGATES TAPESTRY PHARMACEUTICALS, INC. (US) 2006-11-23 WO disclosed
US-20060154251-A1 Carboxamide-substituted dyes for analytical applications ATTO-TEC GMBH (DE) 2006-07-13 US disclosed
US-20050233462-A1 Reagents and a method for saturation labelling of proteins GLOBAL LIFE SCIENCES SOLUTIONS GERMANY GMBH (DE) 2005-10-20 US disclosed
CN-1650168-A Reagents and methods for saturation labelling of proteins AMOSEN BIOLOG SCIENCE BRITISH (GB) 2005-08-03 CN disclosed
EP-1520176-A1 REAGENTS AND A METHOD FOR SATURATION LABELLING OF PROTEINS Amersham Biosciences UK Limited (GB) 2005-04-06 EP disclosed
WO-2004005933-A1 REAGENTS AND A METHOD FOR SATURATION LABELLING OF PROTEINS AMERSHAM BIOSCIENCES UK LIMITED (GB) 2004-01-15 WO disclosed
US-6103236-A IN WHICH A COMPOUND HAVING AN AFFINITY FOR A TARGET CELL IS BOUND TO A TOXIN THROUGH A SPACER CONSISTING ESSENTIALLY OF POLYALKYLENE GLYCOL AND A DIPEPTIDE. KYOWA HAKKO KOGYO CO., LTD. (JP) 2000-08-15 US disclosed
EP-0867190-A1 NOVEL TOXIN COMPLEX KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233462-A1 Reagents and a method for saturation labelling of proteins SET, IK, MRPS22 GABRP 3336/4885GABRD 4019/4885GABRA1 3964/4885
US-20210228494-A1 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN GABRP 1254/4885GABRD 3428/4885GABRA1 2361/4885
US-20060154251-A1 Carboxamide-substituted dyes for analytical applications CPS1, CYCS, PFAS GABRP 1543/4885GABRD 3213/4885GABRA1 1272/4885
US-20220071917-A9 DRUG DELIVERY SYSTEMS AND METHODS COMPRISING POLYSIALIC ACID AND/OR OTHER POLYMERS LNPEP, CLIC1, CLSPN GABRP 1254/4885GABRD 3428/4885GABRA1 2361/4885
US-12472259-B2 PKC inhibitors for the treatment of septic cholestasis with polymethine dye targeting PRKCH, PRKCZ, PIKFYVE GABRP 1317/4885GABRD 3902/4885GABRA1 4497/4885
US-20260102500-A1 PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH POLYMETHINE DYE TARGETING PRKCE, PRKCI, PRKCZ GABRP 1510/4885GABRD 3973/4885GABRA1 4462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.