Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456935 | 0.82 | ABCC9 (0.57) | HTTNPC1KMT2APKMALDH1A1 | |
| SCHEMBL8940750 | 0.81 | ROCK2 (0.44) | FFAR2HTTSMN1; SMN2KMT2AALOX15 | |
| SCHEMBL11078900 | 0.81 | NPC1 (0.60) | FFAR2HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11072102 | 0.79 | ALDH1A1 (0.63) | FFAR2HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11072104 | 0.79 | ALDH1A1 (0.63) | FFAR2HTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11079424 | 0.78 | LMNA (0.56) | SMN1; SMN2KMT2ANOTUMPKMLMNA | |
| SCHEMBL11073535 | 0.77 | TSHR (0.60) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9456838 | 0.76 | ABCC9 (0.51) | RAB9ANPC1KMT2AALOX15ALDH1A1 | |
| SCHEMBL14538107 | 0.76 | NPC1 (0.51) | HTTRAB9ANPC1KMT2ANAMPT | |
| Hydrochloric Acid SCHEMBL10447525 | 0.75 | ABCC9 (0.50) | RAB9ANPC1KMT2AALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381504-A2 | Improvements in and relating to guanidine derivatives | ELI LILLY AND COMPANY (US) | 1990-08-08 | — | — | EP | disclosed |