Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708291 | 0.89 | ALDH1A1 (0.51) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL10452675 | 0.81 | NPSR1 (0.44) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL27826514 | 0.81 | CYP3A4 (0.48) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL60545 | 0.78 | CYP3A4 (0.51) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL10508258 | 0.77 | CES2 (0.46) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL10505584 | 0.76 | ENPP3 (0.48) | NPSR1GAALMNAHTTALDH1A1 | |
| SCHEMBL6980269 | 0.75 | POLB (0.40) | CYP2C19CYP1A2CYP2C9GAALMNA | |
| SCHEMBL7122940 | 0.75 | NPSR1 (0.56) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL10708800 | 0.74 | ALDH1A1 (0.42) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL10507501 | 0.73 | ALDH1A1 (0.49) | CYP3A4CYP2C19CYP1A2CYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274353-B1 | PROCESS FOR THE PREPARATION OF BENZOIN SULFONATES | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| US-4837350-A | Process for the preparation of benzoin sulfonates | CIBA-GEIGY CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |