SCHEMBL1045359

SCHEMBL1045359

CCCCCCCCCCN[C@@H](CC(N)=O)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 11/20 0.42
NOD1 Q9Y239 1/20 0.42
RRM1 P23921 1/20 0.39
CASP2 P42575 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
SOAT1 P35610 1/20 0.38
KMT2A Q03164 1/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
ALOX15 P16050 1/20 0.37
SIRT6 Q8N6T7 1/20 0.37
SIRT1 Q96EB6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23831532 1.00 EPHX1 (0.42) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL1045358 1.00 EPHX1 (0.42) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL29697582 1.00 EPHX1 (0.42) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL2692730 1.00 EPHX1 (0.42) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL29364715 1.00 EPHX1 (0.42) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL7355950 0.98 NOD1 (0.40) EPHX1NOD1RRM1CASP2DPP7
SCHEMBL29697562 0.93 ALOX15 (0.44) EPHX1NOD1DPP7MEN1FAAH
SCHEMBL10927907 0.88 NOD1 (0.50) EPHX1NOD1ALOX15
SCHEMBL10931822 0.88 NOD1 (0.50) EPHX1NOD1ALOX15
SCHEMBL1990412 0.88 NOD1 (0.50) EPHX1NOD1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4262689-B1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE OREAL (FR) 2026-04-08 EP disclosed
US-20240000683-A1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2024-01-04 US disclosed
EP-4262689-A1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2023-10-25 EP disclosed
WO-2022129386-A1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2022-06-23 WO disclosed
US-20160206546-A1 COMPOSITION COMPRISING AN AMINOSILICONE, A CATIONIC SURFACTANT, AN ASSOCIATIVE POLYMER AND A THICKENING AGENT L'OREAL (FR) 2016-07-21 US disclosed
EP-3030324-A1 COMPOSITION COMPRISING AN AMINOSILICONE, A CATIONIC SURFACTANT, AN ASSOCIATIVE POLYMER AND A THICKENING AGENT L'OREAL (FR) 2016-06-15 EP disclosed
WO-2015013779-A1 COMPOSITION COMPRISING AN AMINOSILICONE, A CATIONIC SURFACTANT, AN ASSOCIATIVE POLYMER AND A THICKENING AGENT L'OREAL (FR) 2015-02-05 WO disclosed
EP-1426032-B1 Oxidative dyeing composition for keratinic fibres comprising a non oxyalkylenated fatty alcohol, an oxidation dye, an associative polymer and an amide from an alkanolamine and a C14-C30 fatty acid OREAL (FR) 2011-11-16 EP disclosed
EP-2275082-A1 Composition for oxidation dyeing keratin fibers comprising a nonionic associative polymer, a specific cellulosic compound and a specific cationic polymer. L'Oréal (FR) 2011-01-19 EP disclosed
US-7771491-B2 Oxidation dye composition for keratin fibers, comprising at least one oxidation dye, at least one associative polymer, at least one nonionic cellulose-based compound not comprising a C8-C30 fatty chain, and at least one cationic polymer with a charge density of greater than 1 meq/g and not comprising a C8-C30 fatty chain L'OREAL S.A. (FR) 2010-08-10 US disclosed
US-20040163187-A1 Composition for the oxidation dyeing of keratin fibers, comprising at least one oxidation dye, at least one associative polymer, and at least one aminosilicone L'OREAL S.A. (FR) 2004-08-26 US disclosed
EP-1426039-A1 Oxidative dye composition for keratinic fibers comprising a fatty alcohol, an oxidative dye, an associative polymer, a fatty acid ester and/or a metallic oxide L'OREAL (FR) 2004-06-09 EP disclosed
EP-1426040-A1 Oxidising composition for keratin fibres comprising an oxidising agent, an associative polymer, a nonionic cellulosic compound having no C8-30 fatty chain and a cationic polymer having a charge density greater than 1 meq/g and having no C8-30 fatty chain L'OREAL (FR) 2004-06-09 EP disclosed
EP-1426032-A2 Oxidative dyeing composition for keratinic fibres comprising a non oxyalkylenated fatty alcohol, an oxidation dye, an associative polymer and an amide from an alkanolamine and a C14-C30 fatty acid L'OREAL (FR) 2004-06-09 EP disclosed
EP-1426038-A1 Composition for the oxidative dyeing of keratin fibres containing an oxydation dye, a associative polymer and an amine silicone L'OREAL (FR) 2004-06-09 EP disclosed
US-20030172472-A1 Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain L'OREAL S.A. (FR) 2003-09-18 US disclosed
US-20030074747-A1 Composition for the oxidation dyeing of keratin fibres, comprising at least one fatty alcohol chosen from mono- and polyglycerolated fatty alcohols and a particular polyol L'OREAL S.A. (FR) 2003-04-24 US disclosed
EP-1299072-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN AMPHOTERIC POLYMER WITH FATTY CHAIN L'OREAL (FR) 2003-04-09 EP disclosed
EP-1279395-A1 Composition for oxidative dyeing of keratinous fibres containing a fatty alcohol mono- or poly-glycerols and a particular polyol L'OREAL S.A. (FR) 2003-01-29 EP disclosed
WO-2002000181-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING AN AMPHOTERIC POLYMER WITH FATTY CHAIN L'OREAL (FR) 2002-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040163187-A1 Composition for the oxidation dyeing of keratin fibers, comprising at least one oxidation dye, at least one associative polymer, and at least one aminosilicone KRT18, TUBB1, TUBB3 EPHX1 4264/4885NOD1 4822/4885RRM1 3921/4885
US-20240000683-A1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYEING BASE, AT LEAST ONE GUAR GUM AND AT LEAST ONE FATTY SUBSTANCE NDUFB5, CYB5R3, ADH5 EPHX1 835/4885NOD1 3346/4885RRM1 3008/4885
US-20160206546-A1 COMPOSITION COMPRISING AN AMINOSILICONE, A CATIONIC SURFACTANT, AN ASSOCIATIVE POLYMER AND A THICKENING AGENT KRT18, ALG3, MARK3 EPHX1 4863/4885NOD1 4771/4885RRM1 3874/4885
US-20030172472-A1 Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain KRT18, MB, MDN1 EPHX1 1548/4885NOD1 4771/4885RRM1 3128/4885
US-20030074747-A1 Composition for the oxidation dyeing of keratin fibres, comprising at least one fatty alcohol chosen from mono- and polyglycerolated fatty alcohols and a particular polyol KRT18, FASN, GK EPHX1 2677/4885NOD1 4882/4885RRM1 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.