SCHEMBL10469575

SCHEMBL10469575

CCC(O)COCC(C)C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.34
HTT P42858 2/20 0.33
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL325805 0.89 KDM4E (0.52) KDM4EHSD17B10L3MBTL1TSHRTDP1
Water SCHEMBL27734809 0.86 KDM4E (0.50) KDM4EHSD17B10L3MBTL1TSHRTDP1
SCHEMBL1836147 0.86 KDM4E (0.44) KDM4EHSD17B10L3MBTL1TSHRTDP1
SCHEMBL20041680 0.84 HSD17B10 (0.61) KDM4EHSD17B10L3MBTL1TSHRTDP1
SCHEMBL13108264 0.84 KDM4E (0.44) KDM4EHSD17B10L3MBTL1TSHRTDP1
SCHEMBL16013817 0.80 L3MBTL1 (0.46) KDM4EHSD17B10L3MBTL1TSHRTDP1
Isopropyl Alcohol SCHEMBL7592214 0.80 ALDH1A1 (0.43) KDM4EHSD17B10L3MBTL1TSHRTDP1
SCHEMBL14468244 0.79 KDM4E (0.44) KDM4EHSD17B10TSHRTDP1USP2
SCHEMBL14667423 0.79 KDM4E (0.44) KDM4EHSD17B10TSHRTDP1USP2
SCHEMBL117539 0.79 USP2 (0.48) KDM4EHSD17B10L3MBTL1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239774-A1 SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF CORNELL UNIVERSITY (US) 2024-07-18 US disclosed
US-11384259-B2 Void-containing layer, laminate, method for producing void-containing layer, optical member, and optical apparatus NITTO DENKO CORPORATION (JP) 2022-07-12 US disclosed
US-20200233122-A1 VOID-CONTAINING LAYER, LAMINATE, METHOD FOR PRODUCING VOID-CONTAINING LAYER, OPTICAL MEMBER, AND OPTICAL APPARATUS NITTO DENKO CORPORATION (JP) 2020-07-23 US disclosed
US-20170258741-A1 FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY CATABASIS PHARMACEUTICALS, INC. (US) 2017-09-14 US disclosed
WO-2017024110-A1 POLYMERS DERIVED FROM AMINO-FUNCTIONAL VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-02-09 WO disclosed
WO-2015109130-A1 AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS NOVIRA THERAPEUTICS, INC. (US) 2015-07-23 WO disclosed
WO-2014135390-A1 INK COMPOSITION FOR PRODUCING SEMICONDUCTING THIN FILMS BASF SE (DE) 2014-09-12 WO disclosed
US-4960774-A Cyclic amines and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0345657-A2 Cyclic amines and fungicides containing them BASF Aktiengesellschaft (DE) 1989-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258741-A1 FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY NDUFAB1, ATG7, HADHA KDM4E 3678/4885HSD17B10 838/4885L3MBTL1 2145/4885
US-20240239774-A1 SOLUBLE ADENYLYL CYCLASE (SAC) INHIBITORS AND USES THEREOF UACA, ADCYAP1R1, ADCY1 KDM4E 4664/4885HSD17B10 710/4885L3MBTL1 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.