Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.58 |
| ▸ | ABAT | P80404 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299758 | 1.00 | APP (0.65) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL3205979 | 0.85 | APP (0.65) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL5758511 | 0.82 | ALDH1A1 (0.46) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL13252530 | 0.82 | FDPS (0.47) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL4808158 | 0.81 | ALDH1A3 (0.61) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| SCHEMBL15651545 | 0.79 | FDPS (0.53) | APPALDH1A1TSHRTRIM24HPGD | |
| SCHEMBL8557442 | 0.78 | APP (0.56) | APPALDH1A1TSHRTRIM24HPGD | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL25202 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL1330962 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103251513-A | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | OREAL | 2013-08-21 | — | — | CN | claimed |
| US-8034125-B2 | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | L'OREAL S.A. (FR) | 2011-10-11 | — | — | US | claimed |
| EP-2205681-B1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | OREAL (FR) | 2011-08-31 | — | — | EP | claimed |
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | claimed |
| CN-101802107-A | Dye composition comprising at least one colourless disulfide/thiol precursor and dyeing process using said composition | OREAL | 2010-08-11 | — | — | CN | claimed |
| EP-2205681-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'Oreal (FR) | 2010-07-14 | — | — | EP | claimed |
| WO-2009040354-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL (FR) | 2009-04-02 | — | — | WO | claimed |
| US-6652601-B2 | For dyeing and subsequently decolorizing fibers such as keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-25 | — | — | US | claimed |
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| CN-103251513-A | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | OREAL | 2013-08-21 | — | — | CN | disclosed |
| CN-101558038-B | Curcumin derivative | TOKYO INST TECH | 2013-05-01 | — | — | CN | disclosed |
| CN-102498095-A | Indoline derivatives | TOKYO INST TECH | 2012-06-13 | — | — | CN | disclosed |
| EP-2394990-A1 | INDOLINE DERIVATIVES | Kyoto University (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110294850-A1 | INDOLINE DERIVATIVES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
| CN-101558038-A | Novel curcumin derivative | TOKYO INST TECH (JP) | 2009-10-14 | — | — | CN | disclosed |
| WO-2009040354-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL (FR) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008030072-A1 | COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030072-A1 | COMPOUND FOR INHIBITING THE FORMATION OF BETA-AMYLOID FIBRIL, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | KRT18, SQOR, TST | APP 1179/4885ALDH1A1 743/4885TSHR 3345/4885 |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | APP 2/4885ALDH1A1 253/4885TSHR 4666/4885 |
| US-20110294850-A1 | INDOLINE DERIVATIVES | BCHE, ACHE, INMT | APP 862/4885ALDH1A1 392/4885TSHR 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.