SCHEMBL1050423

SCHEMBL1050423

NC(O)Cc1ccc(O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 1/20 0.69
ALOX15 P16050 8/20 0.61
KDM4E B2RXH2 8/20 0.61
RECQL P46063 8/20 0.61
TDP1 Q9NUW8 7/20 0.61
HIF1A Q16665 5/20 0.61
HSD17B10 Q99714 5/20 0.61
USP2 O75604 2/20 0.61
ADORA3 P0DMS8 2/20 0.61
HTR2A P28223 2/20 0.61
PTGS2 P35354 2/20 0.61
PTGS1 P23219 2/20 0.61
EGFR P00533 2/20 0.61
LCK P06239 1/20 0.61
FYN P06241 1/20 0.61
SLC7A5 Q01650 1/20 0.61
MAPT P10636 6/20 0.61
ALOX12 P18054 4/20 0.61
MAPK1 P28482 4/20 0.61
ALDH1A1 P00352 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5070920 0.98 PLA2G1B (0.67) PLA2G1BALOX15KDM4ERECQLTDP1
Hydrochloric Acid SCHEMBL28352199 0.98 PLA2G1B (0.67) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL17244102 0.84 PLA2G1B (0.65) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL20417370 0.83 PLA2G1B (0.64) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL10893521 0.83 PLA2G1B (0.48) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL11950426 0.83 PLA2G1B (0.64) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL11274987 0.82 PLA2G1B (0.47) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL10804215 0.82 PLA2G1B (0.47) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL633687 0.81 ALOX15 (0.70) PLA2G1BALOX15KDM4ERECQLTDP1
SCHEMBL13660697 0.81 ALOX15 (0.70) PLA2G1BALOX15KDM4ERECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2884962-B1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INT LLC (US) 2019-05-01 EP claimed
US-20150216799-A1 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC 2015-08-06 US claimed
EP-2884962-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS Smartek International LLC (US) 2015-06-24 EP claimed
WO-2014028796-A2 PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS SMARTEK INTERNATIONAL LLC (US) 2014-02-20 WO claimed
US-20070191368-A1 Inhibition of tissue damage to skin from radiation treatment therapy BISSETT DONALD L 2007-08-16 US claimed
US-20250213545-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF NEURODEGENERATIVE DISEASES, COMPRISING FEXOFENADINE STANDIGM INC. (KR) 2025-07-03 US disclosed
US-12303564-B2 Composite chitosan-tannin-active agent compositions and methods of making and using same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-05-20 US disclosed
WO-2024035015-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF NEURODEGENERATIVE DISEASES, COMPRISING FEXOFENADINE 아주대학교산학협력단 2024-02-15 WO disclosed
US-11701360-B2 Composition for inducing differentiation and protection of neural stem cells and method for inducing neuro-regeneration using the same composition Genuv Inc. (KR) 2023-07-18 US disclosed
EP-4180517-A1 PRE-CONDITIONED MESENCHYMAL STEM CELLS AND PREPARATIONS AND APPLICATIONS THEREOF Buddhist Tzu Chi Medical Foundation (TW) 2023-05-17 EP disclosed
CN-116103231-A Preconditioning mesenchymal stem cells, preparation and application thereof 佛教慈济医疗财团法人 2023-05-12 CN disclosed
US-20230145213-A1 Pre-conditioned mesenchymal stem cells and preparations and applications thereof BUDDHIST TZU CHI MEDICAL FOUNDATION (TW) 2023-05-11 US disclosed
EP-1835287-A2 Method and test kits for determining neuroendocrinal diseases Bieger, Wilfried P. (DE) 2007-09-19 EP disclosed
US-20060025385-A1 L-DOPA amide derivatives and uses thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-02-02 US disclosed
US-5081033-A Effective amount of ammonium ions to enhance chlamydospore por duction by strains of Candida albicans WADLEY TECHNOLOGIES, INC. (US) 1992-01-14 US disclosed
US-4847128-A INCUBATION, ANALYZING WADLEY TECHNOLOGIES, INC. (US) 1989-07-11 US disclosed
EP-0160743-B1 MINIATURIZED YEAST IDENTIFICATION SYSTEM Wadley Technologies, Inc. (US) 1989-03-22 EP disclosed
US-4728607-A CULTURE CONTAINER FOR VIEWING UNDER MICROSCOPE J. K. AND SUSIE L. WADLEY RESEARCH INSTITUTE AND BLOOD BANK (US) 1988-03-01 US disclosed
EP-0160743-A2 Miniaturized yeast identification system Wadley Technologies, Inc. (US) 1985-11-13 EP disclosed
US-4144133-A OXGALL, SAPONIN, SUBSTRATE FOR PHENOL OXIDASE J. K. AND SUSIE L. WADLEY RESEARCH INSTITUTE AND BLOOD BANK (US) 1979-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701360-B2 Composition for inducing differentiation and protection of neural stem cells and method for inducing neuro-regeneration using the same composition NOTCH2, NOTCH1, APP PLA2G1B 588/4885ALOX15 775/4885KDM4E 2853/4885
US-20060025385-A1 L-DOPA amide derivatives and uses thereof SNCA, DBH, PARK7 PLA2G1B 1480/4885ALOX15 1467/4885KDM4E 3395/4885
US-12303564-B2 Composite chitosan-tannin-active agent compositions and methods of making and using same TTPA, CHIA, CHIT1 PLA2G1B 694/4885ALOX15 737/4885KDM4E 2781/4885
US-20230145213-A1 Pre-conditioned mesenchymal stem cells and preparations and applications thereof NEFM, EXOSC10, EXOSC5 PLA2G1B 376/4885ALOX15 233/4885KDM4E 3956/4885
US-20250213545-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF NEURODEGENERATIVE DISEASES, COMPRISING FEXOFENADINE SNCA, PARK7, CAT PLA2G1B 3042/4885ALOX15 411/4885KDM4E 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.