Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439684 | 0.83 | ATM (0.45) | ATMCES1CES2F2F10 | |
| SCHEMBL13317140 | 0.80 | CES2 (0.52) | ATMCES1CES2F2F10 | |
| SCHEMBL27544254 | 0.77 | LMNA (0.41) | ATMF2F10F12F7 | |
| SCHEMBL9425725 | 0.77 | PTGS2 (0.57) | CES1CES2F2F10F12 | |
| SCHEMBL25732370 | 0.76 | F2 (0.48) | CES1CES2F2F10F12 | |
| SCHEMBL22641377 | 0.75 | HTT (0.46) | CES1CES2KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22056712 | 0.75 | NAPRT (0.41) | TP53KMT2AMAPTLMNAMEN1 | |
| SCHEMBL14413122 | 0.75 | HPGD (0.50) | KMT2AMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL12599378 | 0.75 | C1S (0.59) | TP53KMT2AC1SMAPTSMN1; SMN2 | |
| SCHEMBL13673789 | 0.74 | F2 (0.52) | CES1F2F10F12F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4207992-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME | LG Display Co., Ltd. (KR) | 2023-07-05 | — | — | EP | disclosed |
| EP-3458439-B1 | 2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE ANALOGS AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO INC (US) | 2021-12-08 | — | — | EP | disclosed |
| US-11192857-B2 | 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine analogs and methods for their synthesis and use | ALERE SAN DIEGO, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20190292148-A1 | 2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE ANALOGS AND METHODS FOR THEIR SYNTHESIS AND USE | ALERE SAN DIEGO, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| EP-3088397-B1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | CANBAS CO LTD (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-10008675-B2 | Organic compound and organic electroluminescent element comprising same | DOOSAN CORPORATION (KR) | 2018-06-26 | — | — | US | disclosed |
| US-20170114013-A1 | LOW CALCEMIC, HIGHLY ANTIPROLIFERATIVE, ANALOGS OF CALCITRIOL | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2017-04-27 | — | — | US | disclosed |
| US-9481646-B2 | Low calcemic, highly antiproliferative, analogs of calcitriol | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160200746-A1 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | UNIV MINNESOTA (US) | 2016-07-14 | — | — | US | disclosed |
| WO-2014113607-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | WO | disclosed |
| US-7951827-B2 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-05-31 | — | — | US | disclosed |
| EP-1869038-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-2-YLAMINE COMPOUNDS AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2009-07-08 | — | — | EP | disclosed |
| EP-0304057-A2 | Pyridinone derivatives, and agricultural and horticultural fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114013-A1 | LOW CALCEMIC, HIGHLY ANTIPROLIFERATIVE, ANALOGS OF CALCITRIOL | VDR, CYP24A1, CYP27B1 | ATM 4262/4885CES1 1585/4885CES2 4268/4885 |
| US-10008675-B2 | Organic compound and organic electroluminescent element comprising same | OR10J3, ORAI2, ETV6 | ATM 997/4885CES1 3918/4885CES2 1276/4885 |
| US-20160200746-A1 | TITANIUM (IV) COMPOUNDS AND METHODS OF FORMING HETEROCYCLIC COMPOUNDS USING SAME | TERT, PIK3C3, TPI1 | ATM 2051/4885CES1 4750/4885CES2 3653/4885 |
| US-11192857-B2 | 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine analogs and methods for their synthesis and use | DPYSL2, DNPEP, DPYSL3 | ATM 4652/4885CES1 3137/4885CES2 3168/4885 |
| US-20190292148-A1 | 2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE ANALOGS AND METHODS FOR THEIR SYNTHESIS AND USE | DPYSL2, DNPEP, DPYSL3 | ATM 4652/4885CES1 3137/4885CES2 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.