SCHEMBL10522149

SCHEMBL10522149

CCOc1ccc([SiH2]CCCc2ccc(F)c(Oc3ccccc3)c2)c(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.34
TTR P02766 1/20 0.34
NTRK1 P04629 1/20 0.34
NTRK3 Q16288 1/20 0.34
NTRK2 Q16620 1/20 0.34
CALM1 P0DP23 2/20 0.33
POLB P06746 1/20 0.33
LTA4H P09960 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801532 0.81 LTA4H (0.43) L3MBTL1TTRLTA4H
SCHEMBL10446712 0.73 PPARG (0.45)
SCHEMBL10737754 0.73 VDR (0.39) L3MBTL1TTRMEN1KMT2A
SCHEMBL10739731 0.72 L3MBTL1 (0.37) L3MBTL1TTRNTRK1NTRK3NTRK2
SCHEMBL10739757 0.72 VDR (0.34) L3MBTL1TTRLTA4H
SCHEMBL14406381 0.72 TTR (0.45) TTR
SCHEMBL10626475 0.72 L3MBTL1 (0.39) L3MBTL1TTRPOLBLTA4H
SCHEMBL10648409 0.71 L3MBTL1 (0.34) L3MBTL1NTRK1NTRK3NTRK2CALM1
SCHEMBL8638059 0.70 TTR (0.44) TTR
SCHEMBL10546364 0.70 CALM1 (0.44) TTRCALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1301606-A None JP disclosed
JP-H01301606-A DUST FORMULATION OR WATER DISPERSIBLE POWDER FOR AGRICULTURE AND HORTICULTURE AND STABILIZATION THEREOF DAINIPPON JOCHUGIKU CO LTD 1989-12-05 JP disclosed