SCHEMBL9801532

SCHEMBL9801532

CCOc1ccc([SiH2]CCCc2ccc(F)c(Oc3ccccc3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.43
SIGMAR1 Q99720 1/20 0.37
CACNA1C Q13936 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LPAR1 Q92633 4/20 0.35
LPAR5 Q9H1C0 4/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
TTR P02766 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522149 0.81 L3MBTL1 (0.34) LTA4HL3MBTL1TTR
Silafluofen SCHEMBL27295 0.79 LTA4H (0.43) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4
SCHEMBL393264 0.79 LTA4H (0.43) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4
SCHEMBL6506489 0.79 SIGMAR1 (0.46) LTA4HSIGMAR1CACNA1CLPAR1LPAR5
Silafluofen SCHEMBL8880052 0.79 LTA4H (0.43) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4
SCHEMBL10549602 0.78 LTA4H (0.42) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4
SCHEMBL9558575 0.78 LTA4H (0.41) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4
SCHEMBL10549349 0.78 LTA4H (0.41) LTA4HSIGMAR1CACNA1CLPAR1LPAR5
SCHEMBL9558447 0.78 LTA4H (0.41) LTA4HSIGMAR1CACNA1CLPAR1LPAR5
SCHEMBL407786 0.78 LTA4H (0.41) LTA4HSIGMAR1CACNA1CSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2172993-A None JP disclosed
JP-3099003-A None JP disclosed
JP-H0399003-A TERMITE-CONTROLLING AGENT DAINIPPON JOCHUGIKU CO LTD 1991-04-24 JP disclosed
JP-H02172993-A MOTH-PROOFING AGENT DAINIPPON JOCHUGIKU CO LTD 1990-07-04 JP disclosed