Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544818 | 0.86 | CALM1 (0.44) | MAOAMAOBELANEIDH1SMN1; SMN2 | |
| SCHEMBL10548359 | 0.84 | PTPN5 (0.36) | MAOAMAOBPTPN5HDAC4MEF2D | |
| SCHEMBL11400148 | 0.80 | MAOA (0.59) | MAOAMAOBPTPN5NFE2L2LOXL2 | |
| SCHEMBL16504800 | 0.76 | LOXL2 (0.50) | MAOAMAOBPTPN5LOXL2CYP17A1 | |
| SCHEMBL525893 | 0.75 | NFE2L2 (0.58) | NFE2L2CYP3A4MAPK1NPC1MAPT | |
| SCHEMBL10543807 | 0.75 | ENPP2 (0.46) | MAOAMAOBPTPN5LOXL2CYP17A1 | |
| SCHEMBL7929350 | 0.73 | TAAR1 (0.52) | MAOBPTPN5LOXL2CYP17A1CYP3A4 | |
| SCHEMBL10836716 | 0.71 | XDH (0.39) | CYP3A4LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL10550570 | 0.71 | ALDH1A1 (0.47) | MAOAMAOBNFE2L2CYP3A4LMNA | |
| SCHEMBL10547691 | 0.71 | MAOA (0.40) | MAOAMAOBNFE2L2HDAC4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |