Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546055 | 0.84 | MLYCD (0.51) | MLYCDALDH1A1LMNALTB4RLTB4R2 | |
| SCHEMBL10544853 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL10546095 | 0.77 | KMT2A (0.44) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL8472943 | 0.76 | LTB4R (0.55) | MLYCDLTB4RLTB4R2NPY5RTAAR1 | |
| SCHEMBL10546758 | 0.75 | RIPK1 (0.51) | ALDH1A1LMNATAAR1MEN1MAPT | |
| SCHEMBL12133560 | 0.74 | MLYCD (0.72) | MLYCDTAAR1MEN1KMT2A | |
| SCHEMBL10546564 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL10547048 | 0.73 | TP53 (0.48) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10544009 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1520363 | 0.71 | KMT2A (0.59) | MLYCDLTB4RLTB4R2NPY5RTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814341-A | HISTAMINE H2 ANTAGONISTS | REITER LAWRENCE A (US) | 1989-03-21 | — | — | US | disclosed |